ATP6V1B2

Gene Name		ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Lysosomal Membrane Cytosol Plasma Membrane Microvillus Endomembrane System Integral Component Of Membrane Proton-transporting V-type ATPase, V1 Domain Melanosome Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	ATP Binding Hydrogen Ion Transmembrane Transporter Activity Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Cellular Iron Ion Homeostasis Insulin Receptor Signaling Pathway ATP Hydrolysis Coupled Proton Transport Proton Transport Transferrin Transport ATP Metabolic Process Interaction With Host Transmembrane Transport Phagosome Maturation
Pathways		Phagosomal maturation (early endosomal stage) Iron uptake and transport Latent infection of Homo sapiens with Mycobacterium tuberculosis Transferrin endocytosis and recycling Insulin receptor recycling Signaling by Insulin receptor
Drugs
Diseases
GWAS		Circulating myeloperoxidase levels (serum) ( 23620142) Major depressive disorder (broad) ( 20038947)
Protein-protein Interactions		1 interactors: TCF4
Entrez ID		526
HPRD ID		06088
Ensembl ID		ENSG00000147416
Uniprot IDs		P21281
PDB IDs
Enriched GO Terms of Interacting Partners?		Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Maintenance Of DNA Repeat Elements Embryonic Hindgut Morphogenesis Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Embryonic Genitalia Morphogenesis Myoblast Fate Commitment Secretory Granule Localization Hindgut Morphogenesis Insulin Metabolic Process Hindgut Development Positive Regulation Of Protein Export From Nucleus Positive Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Gluconeogenesis Regulation Of Triglyceride Biosynthetic Process Genitalia Morphogenesis Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Embryonic Digestive Tract Morphogenesis Regulation Of Glycoprotein Biosynthetic Process Regulation Of Protein Export From Nucleus Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Glucose Metabolic Process Regulation Of Triglyceride Metabolic Process Regulation Of Hormone Metabolic Process Face Morphogenesis Negative Regulation Of Organ Growth Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Head Morphogenesis Oligodendrocyte Development Embryonic Digestive Tract Development Negative Regulation Of BMP Signaling Pathway Regulation Of Oligodendrocyte Differentiation Myoblast Differentiation Regulation Of Gluconeogenesis Bone Mineralization Regulation Of Myelination Face Development Positive Regulation Of Stem Cell Differentiation Pituitary Gland Development Regulation Of Epithelial To Mesenchymal Transition Genitalia Development Negative Regulation Of Fat Cell Differentiation Body Morphogenesis Positive Regulation Of Lipid Biosynthetic Process Glycogen Metabolic Process Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Insulin Secretion
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