PGA5

Description		pepsinogen A5
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Exosome Multivesicular Body Lumen
	Molecular Function	Aspartic-type Endopeptidase Activity Peptidase Activity Hydrolase Activity
	Biological Process	Proteolysis Digestion
Pathways		Surfactant metabolism
Drugs		Sucralfate
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: RELA
Interacting Genes
Entrez ID		5222
HPRD ID		01356
Ensembl ID		ENSG00000256713
Uniprot IDs		P0DJD9
PDB IDs
Enriched GO Terms of Interacting Partners?		NF-kappaB P50/p65 Complex Toll-like Receptor TLR6:TLR2 Signaling Pathway Regulation Of Schwann Cell Differentiation Positive Regulation Of Schwann Cell Differentiation NF-kappaB Complex Prolactin Signaling Pathway Response To Cobalamin Positive Regulation Of Amyloid-beta Formation Response To Interleukin-6 RNA Polymerase II Core Promoter Sequence-specific DNA Binding Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Vascular Endothelial Growth Factor Signaling Pathway Cellular Response To Lipoteichoic Acid Ankyrin Repeat Binding Actinin Binding Response To Peptidoglycan Phosphate Ion Binding Postsynapse To Nucleus Signaling Pathway Positive Regulation Of T Cell Receptor Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cellular Response To Peptidoglycan Defense Response To Tumor Cell General Transcription Initiation Factor Binding Cellular Response To Interleukin-6 Negative Regulation Of Protein Sumoylation Response To Hepatocyte Growth Factor Response To Morphine Cellular Response To Angiotensin Cellular Response To Hepatocyte Growth Factor Stimulus Response To Muramyl Dipeptide Cellular Response To Nicotine Response To UV-B Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Regulation Of Protein Sumoylation Response To Muscle Stretch Negative Regulation Of MiRNA Transcription Interleukin-1-mediated Signaling Pathway Positive Regulation Of Antigen Receptor-mediated Signaling Pathway Response To Angiotensin Positive Regulation Of Amyloid Precursor Protein Catabolic Process Peptide Binding Positive Regulation Of Amide Metabolic Process Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Vascular Endothelial Growth Factor Production NF-kappaB Binding Negative Regulation Of Non-canonical NF-kappaB Signal Transduction Response To Progesterone Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Signal Transduction Involved In Regulation Of Gene Expression Positive Regulation Of Glial Cell Differentiation
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