PEPD

Gene Name		peptidase D
Image
Gene Ontology Annotations	Cellular Component	Extracellular Vesicular Exosome
	Molecular Function	Aminopeptidase Activity Metallocarboxypeptidase Activity Dipeptidase Activity Manganese Ion Binding
	Biological Process	Proteolysis Cellular Amino Acid Metabolic Process Collagen Catabolic Process
Pathways
Drugs
Diseases
GWAS		Adiponectin levels ( 22479202) Fasting insulin-related traits (interaction with BMI) ( 22581228) Type 2 diabetes ( 22158537)
Protein-protein Interactions		4 interactors: ATXN1 SPP1 TERF1 USP7
Entrez ID		5184
HPRD ID		01358
Ensembl ID		ENSG00000124299
Uniprot IDs		P12955
PDB IDs		2IW2 2OKN
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of Proteasomal Protein Catabolic Process Telomeric Loop Formation Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Maintenance Of DNA Methylation Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Replicative Cell Aging Regulation Of Protein Catabolic Process Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Microtubule Polymerization Regulation Of Telomerase Activity Positive Regulation Of Bone Resorption Developmental Process Regulation Of Axon Regeneration Histone Deubiquitination Regulation Of Telomere Maintenance RNA-dependent DNA Replication Chromatin Modification Negative Regulation Of DNA Biosynthetic Process Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Proteolysis Regulation Of Microtubule Polymerization Positive Regulation Of Tissue Remodeling Decidualization Response To Vitamin D Chromatin Organization Telomere Maintenance Via Telomere Lengthening Mitotic Spindle Assembly Checkpoint Regulation Of Bone Resorption Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Maternal Placenta Development Regulation Of Bone Remodeling Regulation Of DNA Biosynthetic Process Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division
Tagcloud ?		apoc2 atp1a3 bckdha cgb cgm2 cyp2a d19s112 d19s116 d19s117 d19s118 d19s119 d19s19 d19s2 d19s37 d19s50 d19s51 d19s54 d19s55 d19s6 d19s62 d19s63 d19s7 d19s8 d19s9 manb prkcg psg1 pw39 tnnt1