OTUD6B

Description		OTU deubiquitinase 6B
Image		No pdb structure
GO Annotations	Cellular Component	Eukaryotic Translation Initiation Factor 4F Complex
	Molecular Function	Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity
	Biological Process	Proteolysis Cell Population Proliferation Protein Deubiquitination Negative Regulation Of Translation Proteasome Assembly Positive Regulation Of Translation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		6 interacting genes: LIN28B NEDD8 OTUB1 SMURF1 UBC VHL
Entrez ID		51633
HPRD ID		13041
Ensembl ID		ENSG00000155100
Uniprot IDs		A0A087X0W9 Q8N6M0
PDB IDs
Enriched GO Terms of Interacting Partners?		Macromolecule Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Post-translational Protein Modification Catabolic Process Proteolysis Protein Tag Activity Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Modification Process Ubiquitin Protein Ligase Binding Nucleoplasm Negative Regulation Of TORC1 Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Engulfment Of Target By Autophagosome Negative Regulation Of TOR Signaling Proteasomal Protein Catabolic Process Macromolecule Metabolic Process Regulation Of TORC1 Signaling Protein Metabolic Process Protein Catabolic Process Cytosol Negative Regulation Of Primary MiRNA Processing Negative Regulation Of Pre-miRNA Processing Regulation Of TOR Signaling Cellular Response To Camptothecin Ubiquitin-protein Transferase Inhibitor Activity DeNEDDylase Activity Activin Receptor Binding Positive Regulation Of MiRNA Catabolic Process Extracellular Exosome Transcription Elongation Factor Activity Substrate Localization To Autophagosome Negative Regulation Of MiRNA Processing Ubiquitin-protein Transferase Activity MiRNA Catabolic Process Cytoplasm I-SMAD Binding Protein Targeting To Vacuole Involved In Autophagy Ectoderm Development Negative Regulation Of Activin Receptor Signaling Pathway Transforming Growth Factor Beta Receptor Binding Negative Regulation Of Post-transcriptional Gene Silencing By Regulatory NcRNA Negative Regulation Of MiRNA-mediated Gene Silencing Regulation Of MiRNA Processing Pre-miRNA Processing Regulation Of Regulatory NcRNA Processing Receptor Catabolic Process Regulation Of Proteolysis
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