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PDE7A

Description phosphodiesterase 7A
Image
GO Annotations Cellular Component
  • Cytoplasm
  • Cytosol
Molecular Function
  • Cyclic-nucleotide Phosphodiesterase Activity
  • 3',5'-cyclic-nucleotide Phosphodiesterase Activity
  • 3',5'-cyclic-AMP Phosphodiesterase Activity
  • Phosphoric Diester Hydrolase Activity
  • Hydrolase Activity
  • Metal Ion Binding
  • 3',5'-cyclic-GMP Phosphodiesterase Activity
Biological Process
  • CAMP Catabolic Process
  • Signal Transduction
  • Negative Regulation Of CAMP/PKA Signal Transduction
Pathways
  • G alpha (s) signalling events
Drugs
  • Caffeine
  • 3-isobutyl-1-methyl-7H-xanthine
  • 3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one
  • Trapidil
Diseases
GWAS
  • Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)
  • Metabolite levels ( 23823483)
  • Right lateral prefrontal cortical growth ( 29682794)
Interacting Genes 1 interacting genes: UBASH3A
Entrez ID 5150
HPRD ID 01386
Ensembl ID ENSG00000205268
Uniprot IDs Q13946
PDB IDs 1ZKL 3G3N 4PM0 4Y2B
Enriched GO Terms of Interacting Partners?
  • Negative Regulation Of T Cell Receptor Signaling Pathway
  • Regulation Of T Cell Receptor Signaling Pathway
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© Madhavi K. Ganapathiraju 2012-2025