ACTL6B

Description		actin like 6B
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Chromatin Nucleus Nuclear Matrix SWI/SNF Complex RSC-type Complex Brahma Complex NuA4 Histone Acetyltransferase Complex NBAF Complex BBAF Complex GBAF Complex
	Molecular Function	Chromatin Binding Transcription Coactivator Activity Structural Constituent Of Cytoskeleton
	Biological Process	Chromatin Organization Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Cytoskeleton Organization Nervous System Development Positive Regulation Of Cell Population Proliferation Dendrite Development Regulation Of Mitotic Metaphase/anaphase Transition Neuron Maturation Positive Regulation Of T Cell Differentiation Negative Regulation Of Cell Differentiation Positive Regulation Of Cell Differentiation Positive Regulation Of Myoblast Differentiation Positive Regulation Of DNA-templated Transcription Regulation Of G0 To G1 Transition Positive Regulation Of Stem Cell Population Maintenance Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Double-strand Break Repair Regulation Of Nucleotide-excision Repair
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Drugs
Diseases
GWAS		Hematocrit ( 28017375 29403010) Hemoglobin levels ( 28017375) Mean corpuscular hemoglobin ( 28017375 32888494) Mean corpuscular volume ( 28017375 29403010 32888494) Red blood cell count ( 28017375) Red blood cell traits ( 23222517) Red cell distribution width ( 28957414)
Interacting Genes		12 interacting genes: ANXA7 APP ATM CDKN1A COQ9 CSNK2B CTBP1 GSK3B PLK1 SMARCA2 SMN1 TK1
Entrez ID		51412
HPRD ID		12419
Ensembl ID		ENSG00000077080
Uniprot IDs		O94805
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Population Proliferation Regulation Of Cell Cycle Mitotic G2 DNA Damage Checkpoint Signaling Peptidyl-serine Phosphorylation Protein Phosphorylation Phosphorylation Negative Regulation Of Macromolecule Metabolic Process Mitotic G2/M Transition Checkpoint Negative Regulation Of Metabolic Process Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of Cell Cycle G2/M Phase Transition Mitotic DNA Integrity Checkpoint Signaling Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Mitotic DNA Damage Checkpoint Signaling Regulation Of Cellular Response To Stress Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Mitotic Metaphase/anaphase Transition DNA Damage Checkpoint Signaling Negative Regulation Of Gene Expression Regulation Of G2/M Transition Of Mitotic Cell Cycle Replicative Senescence Regulation Of Sister Chromatid Segregation Regulation Of Cellular Response To Heat Identical Protein Binding Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Protein Catabolic Process Regulation Of Chromosome Segregation Regulation Of Proteolysis Negative Regulation Of DNA Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Serine/threonine Kinase Binding Nucleus Molecular Function Activator Activity Regulation Of Protein Localization To Nucleus Regulation Of Double-strand Break Repair Phosphate-containing Compound Metabolic Process Signal Transduction In Response To DNA Damage Protein Serine/threonine Kinase Activity Protein Localization To Site Of Double-strand Break Mitotic Cell Cycle Phase Transition Viral Process Cellular Response To Gamma Radiation Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Cell Cycle Phase Transition Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition
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