BIN2

Gene Name		bridging integrator 2
Image
Gene Ontology Annotations	Cellular Component	Phagocytic Cup Podosome Cell Cortex Cell Junction Cell Projection
	Molecular Function	Protein Binding Phospholipid Binding
	Biological Process	Phagocytosis, Engulfment Cell Chemotaxis Podosome Assembly Membrane Tubulation
Pathways
Drugs
Diseases
GWAS		Aging (time to death) ( 21782286)
Protein-protein Interactions		3 interactors: POT1 TERF1 TINF2
Entrez ID		51411
HPRD ID		05805
Ensembl ID		ENSG00000110934
Uniprot IDs		F5H0W4 Q9UBW5
PDB IDs		4AVM 4I1Q
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Replication Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Regulation Of DNA Replication Telomere Assembly Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Regulation Of Chromosome Organization Regulation Of Telomerase Activity RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Positive Regulation Of Organelle Organization Regulation Of DNA Biosynthetic Process Regulation Of Organelle Organization Chromosome Organization DNA Metabolic Process Positive Regulation Of DNA Metabolic Process Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of DNA Strand Elongation Negative Regulation Of Biosynthetic Process Homeostatic Process Regulation Of Protein ADP-ribosylation Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Telomere Formation Via Telomerase Age-dependent Telomere Shortening DNA Replication Telomere Maintenance Via Telomere Shortening Negative Regulation Of Protein Glycosylation Negative Regulation Of Transferase Activity Cellular Component Assembly Regulation Of Cellular Component Organization Positive Regulation Of Helicase Activity Telomere Capping Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Telomerase Activity Positive Regulation Of Telomere Maintenance Via Telomerase Replicative Cell Aging Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Protein Glycosylation Negative Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Microtubule Polymerization
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