ANGPT4

Gene Name		angiopoietin 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Activator Activity Receptor Tyrosine Kinase Binding
	Biological Process	Angiogenesis Endothelial Cell Proliferation Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity Blood Coagulation Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Apoptotic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Angiogenesis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Leukocyte Migration Cellular Response To Hypoxia
Pathways		Tie2 Signaling Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: TEK TIE1
Entrez ID		51378
HPRD ID		04747
Ensembl ID		ENSG00000101280
Uniprot IDs		B4E3J9 Q9Y264
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Angiogenesis Regulation Of Angiogenesis Peptidyl-tyrosine Phosphorylation Angiogenesis Blood Vessel Morphogenesis Positive Regulation Of Cytokine Secretion Involved In Immune Response Tie Signaling Pathway Blood Vessel Development Vasculature Development Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Cellular Component Movement Regulation Of Cytokine Secretion Involved In Immune Response Positive Regulation Of Actin Cytoskeleton Reorganization Response To Lipid Heart Trabecula Formation Cardiovascular System Development Endothelial Cell Proliferation Plasma Membrane Fusion Peptidyl-amino Acid Modification Definitive Hemopoiesis Anatomical Structure Formation Involved In Morphogenesis Negative Regulation Of Endothelial Cell Apoptotic Process Positive Regulation Of Focal Adhesion Assembly Positive Regulation Of Adherens Junction Organization Heart Trabecula Morphogenesis Positive Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Vascular Permeability Regulation Of Endothelial Cell Apoptotic Process Protein Phosphorylation Regulation Of Actin Cytoskeleton Reorganization Regulation Of Establishment Or Maintenance Of Cell Polarity Regulation Of NIK/NF-kappaB Signaling Endochondral Ossification Substrate Adhesion-dependent Cell Spreading Regulation Of Focal Adhesion Assembly Positive Regulation Of Cytokine Production Involved In Immune Response Trabecula Morphogenesis Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Cell-matrix Adhesion Sprouting Angiogenesis Positive Regulation Of Endothelial Cell Migration Regulation Of Lipid Kinase Activity Regulation Of Cell Junction Assembly Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Cytokine Production Involved In Immune Response Organ Regeneration Phosphorylation
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