ANGPT4

Description		angiopoietin 4
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Activator Activity Receptor Tyrosine Kinase Binding
	Biological Process	Angiogenesis Endothelial Cell Proliferation Signal Transduction Notch Signaling Pathway Blood Coagulation Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Apoptotic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Angiogenesis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Cellular Response To Hypoxia
Pathways		Tie2 Signaling
Drugs
Diseases
GWAS		Food allergy ( 29030101) Intracranial aneurysm ( 29531279) Logical memory (immediate recall) in Alzheimer's disease dementia ( 29274321) Lung function ( 31902109) Peanut allergy ( 29030101)
Interacting Genes		3 interacting genes: RHOU TEK TIE1
Entrez ID		51378
HPRD ID		04747
Ensembl ID		ENSG00000101280
Uniprot IDs		Q9Y264
PDB IDs
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Kinase Activity Regulation Of Cell-substrate Junction Organization Blood Vessel Development Regulation Of Anatomical Structure Morphogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Angiogenesis Protein Tyrosine Kinase Activity Regulation Of Endothelial Cell Proliferation Branching Involved In Lymph Vessel Morphogenesis Positive Regulation Of Vasculature Development Positive Regulation Of Angiogenesis Receptor Complex Tie Signaling Pathway Nucleotide Binding Regulation Of Angiogenesis Glomerulus Vasculature Development Regulation Of Small GTPase Mediated Signal Transduction Angiogenesis Regulation Of Vasculature Development Lymphatic Endothelial Cell Differentiation Regulation Of Epithelial Cell Proliferation Positive Regulation Of Focal Adhesion Disassembly Anchoring Junction Focal Adhesion Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Heart Trabecula Formation Protein Kinase Activity Regulation Of Developmental Process Definitive Hemopoiesis Regulation Of Cellular Component Organization Positive Regulation Of Rac Protein Signal Transduction Plasma Membrane Fusion Kinase Activity Regulation Of Extracellular Matrix Assembly Enzyme-linked Receptor Protein Signaling Pathway Rac Protein Signal Transduction Regulation Of Establishment Or Maintenance Of Cell Polarity Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Focal Adhesion Assembly Endothelial Cell Differentiation Sprouting Angiogenesis Negative Regulation Of Endothelial Cell Apoptotic Process Endothelial Cell Proliferation Regulation Of Rac Protein Signal Transduction Anatomical Structure Formation Involved In Morphogenesis Aortic Valve Morphogenesis Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Positive Regulation Of Protein Targeting To Mitochondrion Podosome Regulation Of Protein Targeting To Mitochondrion
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