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CHST15
Gene Name
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Integral Component Of Membrane
Molecular Function
3'-phosphoadenosine 5'-phosphosulfate Binding
N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase Activity
Biological Process
Carbohydrate Metabolic Process
Pathogenesis
Hexose Biosynthetic Process
Glycosaminoglycan Metabolic Process
Chondroitin Sulfate Metabolic Process
Chondroitin Sulfate Biosynthetic Process
Small Molecule Metabolic Process
Pathways
MPS IIIB - Sanfilippo syndrome B
Diseases of glycosylation
Defective B4GALT7 causes EDS, progeroid type
MPS I - Hurler syndrome
MPS IX - Natowicz syndrome
Chondroitin sulfate/dermatan sulfate metabolism
Defective SLC26A2 causes chondrodysplasias
Glycosaminoglycan metabolism
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
Defective CHST14 causes EDS, musculocontractural type
Defective PAPSS2 causes SEMD-PA
MPS IIIA - Sanfilippo syndrome A
Myoclonic epilepsy of Lafora
Defective CHST6 causes MCDC1
Glycogen storage diseases
MPS IIID - Sanfilippo syndrome D
Chondroitin sulfate biosynthesis
MPS IIIC - Sanfilippo syndrome C
Diseases associated with glycosaminoglycan metabolism
Mucopolysaccharidoses
Defective EXT2 causes exostoses 2
MPS II - Hunter syndrome
Defective B3GAT3 causes JDSSDHD
Defective CHST3 causes SEDCJD
Defective EXT1 causes exostoses 1, TRPS2 and CHDS
MPS IV - Morquio syndrome A
Defective CHSY1 causes TPBS
MPS IV - Morquio syndrome B
MPS VII - Sly syndrome
Metabolism of carbohydrates
MPS VI - Maroteaux-Lamy syndrome
Drugs
Diseases
GWAS
Protein-protein Interactions
3 interactors:
HCK
LYN
RRAGD
Entrez ID
51363
HPRD ID
12203
Ensembl ID
ENSG00000182022
Uniprot IDs
B4DH74
Q7LFX5
PDB IDs
Enriched GO Terms of Interacting Partners
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Peptidyl-tyrosine Autophosphorylation
Lipopolysaccharide-mediated Signaling Pathway
Cellular Response To Organonitrogen Compound
Leukocyte Degranulation
Regulated Secretory Pathway
Response To Organonitrogen Compound
Response To Amino Acid
Positive Regulation Of Oligodendrocyte Progenitor Proliferation
Respiratory Burst After Phagocytosis
Negative Regulation Of Mast Cell Proliferation
Cellular Response To Lipopolysaccharide
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Cellular Response To Molecule Of Bacterial Origin
Cellular Response To Acid Chemical
Protein Autophosphorylation
Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway
Leukocyte Migration Involved In Immune Response
Cellular Response To Extracellular Stimulus
Leukocyte Migration
Tolerance Induction To Self Antigen
Fc Receptor Mediated Inhibitory Signaling Pathway
Positive Regulation Of Dendritic Cell Apoptotic Process
Phagocytosis
Fc Receptor Signaling Pathway
Regulation Of Inflammatory Response
Immune Response-activating Cell Surface Receptor Signaling Pathway
Peptidyl-tyrosine Phosphorylation
Response To External Stimulus
Cellular Response To Organic Substance
Cellular Response To Peptide Hormone Stimulus
Response To Lipopolysaccharide
Cellular Response To Peptide
Negative Regulation Of Toll-like Receptor 2 Signaling Pathway
Immune Response-inhibiting Cell Surface Receptor Signaling Pathway
Respiratory Burst Involved In Defense Response
Response To Molecule Of Bacterial Origin
Exocytosis
Immune Response-inhibiting Signal Transduction
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Vesicle-mediated Transport
Regulation Of Podosome Assembly
Negative Regulation Of Toll-like Receptor 4 Signaling Pathway
Tolerance Induction
Positive Regulation Of Mast Cell Proliferation
Cellular Response To Lipid
Inflammatory Response
Positive Regulation Of B Cell Receptor Signaling Pathway
Cellular Localization
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