GMPR2

Description		guanosine monophosphate reductase 2
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GO Annotations	Cellular Component	Cytosol GMP Reductase Complex
	Molecular Function	Catalytic Activity GMP Reductase Activity Protein Binding Oxidoreductase Activity Metal Ion Binding
	Biological Process	Purine Nucleobase Metabolic Process Purine Nucleotide Metabolic Process Nucleotide Metabolic Process GMP Metabolic Process
Pathways		Purine salvage
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Refractive error ( 32231278)
Interacting Genes		3 interacting genes: ADRB2 ERBB2 MEOX2
Entrez ID		51292
HPRD ID		13590
Ensembl ID		ENSG00000100938
Uniprot IDs		H0YNJ6 Q6PKC0 Q9P2T1
PDB IDs		2A7R 2BZN 2C6Q
Enriched GO Terms of Interacting Partners?		Response To Psychosocial Stress Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Receptor Complex Beta-adrenergic Receptor Activity Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Norepinephrine Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Lipophagy Positive Regulation Of DNA-templated Transcription Endosome Membrane Positive Regulation Of Mini Excitatory Postsynaptic Potential AMPA Selective Glutamate Receptor Signaling Pathway Beta2-adrenergic Receptor Activity Negative Regulation Of Immature T Cell Proliferation In Thymus RNA Polymerase I Core Binding ErbB-3 Class Receptor Binding ERBB3:ERBB2 Complex Immature T Cell Proliferation In Thymus ERBB2-ERBB4 Signaling Pathway Somite Specification Early Endosome Negative Regulation Of Immature T Cell Proliferation Positive Regulation Of Autophagosome Maturation Heat Generation Positive Regulation Of RNA Metabolic Process Apical Plasma Membrane Positive Regulation Of Nucleobase-containing Compound Metabolic Process Adrenergic Receptor Activity ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB2-EGFR Signaling Pathway ERBB4 Signaling Pathway Diet Induced Thermogenesis Negative Regulation Of T Cell Differentiation In Thymus Positive Regulation Of MAPK Cascade Adenylate Cyclase Binding Negative Regulation Of Smooth Muscle Contraction Regulation Of Immature T Cell Proliferation In Thymus Negative Regulation Of Multicellular Organism Growth Semaphorin Receptor Complex Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Regulation Of Autophagosome Maturation Positive Regulation Of CAMP/PKA Signal Transduction Segment Specification Somite Development Positive Regulation Of Macromolecule Biosynthetic Process Schwann Cell Development Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Positive Regulation Of Biosynthetic Process Regulation Of Growth
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