DNAJC27

Description		DnaJ heat shock protein family (Hsp40) member C27
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GO Annotations	Cellular Component	Nucleus Organelle Membrane Cytoplasmic Vesicle
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Intracellular Protein Transport Positive Regulation Of ERK1 And ERK2 Cascade
Pathways
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Body mass index ( 22344219 26426971 28892062) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Crohn's disease ( 28067908) Height ( 20881960 31562340) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Obese vs. thin ( 30677029) Obesity (extreme) ( 30677029) Pre-treatment viral load in HIV-1 infection ( 31219150) Pubertal anthropometrics ( 23449627) Type 1 diabetes ( 21980299)
Novel Interacting Genes		2 novel interacting genes: IFT172 RAB10
Interacting Genes
Entrez ID		51277
HPRD ID		15221
Ensembl ID		ENSG00000115137
Uniprot IDs		Q9NZQ0
PDB IDs		2YS8
Enriched GO Terms of Interacting Partners?		Protein Localization To Basolateral Plasma Membrane Establishment Of Neuroblast Polarity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Hindgut Development Sperm Cytoplasmic Droplet Intraciliary Transport Particle Insulin-responsive Compartment Cilium Secretory Vesicle Neural Tube Formation Cadherin Binding Involved In Cell-cell Adhesion Endoplasmic Reticulum Tubular Network Organization Exocytic Vesicle Myosin V Binding Exocyst Endoplasmic Reticulum Tubular Network Polarized Epithelial Cell Differentiation Embryonic Epithelial Tube Formation Left/right Axis Specification Negative Regulation Of Keratinocyte Proliferation Intraciliary Transport Particle B Embryonic Eye Morphogenesis Embryonic Camera-type Eye Morphogenesis Spinal Cord Motor Neuron Differentiation Intraciliary Anterograde Transport Sperm Principal Piece Keratinocyte Proliferation Golgi To Plasma Membrane Protein Transport Cell Projection Organization Establishment Of Protein Localization To Endoplasmic Reticulum Epithelial Tube Formation Negative Regulation Of Smoothened Signaling Pathway Cell Differentiation In Spinal Cord Positive Regulation Of Smoothened Signaling Pathway Intracellular Transport Neural Tube Development Cell Projection Ciliary Tip Regulation Of Keratinocyte Proliferation Intraciliary Transport Sperm Midpiece Non-motile Cilium Assembly Digestive Tract Development Limb Development Endoplasmic Reticulum Organization Cellular Localization Anatomical Structure Morphogenesis Establishment Of Protein Localization To Plasma Membrane Establishment Of Localization In Cell Golgi To Plasma Membrane Transport
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