RAPGEFL1

Gene Name		Rap guanine nucleotide exchange factor (GEF)-like 1
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Gene Ontology Annotations	Cellular Component	Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity
	Biological Process	G-protein Coupled Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Nervous System Development Positive Regulation Of GTPase Activity
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: APP MLH1
Entrez ID		51195
HPRD ID		17954
Ensembl ID		ENSG00000108352
Uniprot IDs		Q9UHV5
PDB IDs		2DHZ
Enriched GO Terms of Interacting Partners?		MRNA 3'-end Processing RNA 3'-end Processing Meiotic Spindle Midzone Assembly Meiotic Metaphase I Plate Congression Negative Regulation Of Mitotic Recombination Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation MRNA Processing Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis MRNA Metabolic Process Axon Choice Point Recognition RNA Processing Spindle Midzone Assembly Neuron Remodeling Cell Activation Resolution Of Meiotic Recombination Intermediates Microtubule-based Process Sexual Reproduction Somatic Hypermutation Of Immunoglobulin Genes Somatic Diversification Of Immune Receptors Via Somatic Mutation Cellular Copper Ion Homeostasis Apoptotic Process Double-strand Break Repair Via Nonhomologous End Joining Chromosome Separation Negative Regulation Of DNA Recombination Copper Ion Homeostasis Suckling Behavior Programmed Cell Death Reproduction Nuclear-transcribed MRNA Poly(A) Tail Shortening Cell Death Death Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Isotype Switching Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Metaphase Plate Congression Mating Behavior Somatic Recombination Of Immunoglobulin Gene Segments Endoplasmic Reticulum Calcium Ion Homeostasis Immune Response Somatic Diversification Of Immunoglobulins RNA Polyadenylation Neuron Recognition Reproductive Process
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