CYB5R4

Name	cytochrome b5 reductase 4
Structure
Interactors	1 interactors: PAXIP1
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H NAD(P)H Oxidase H2O2-forming Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On NAD(P)H, Heme Protein As Acceptor Heme Binding Metal Ion Binding
	Biological Process	Detection Of Oxygen Superoxide Metabolic Process Bicarbonate Transport Insulin Secretion Glucose Homeostasis Response To Antibiotic Cell Development Reactive Oxygen Species Metabolic Process
Pathways	Erythrocytes take up carbon dioxide and release oxygen
GWAS	Femur bone mineral density x serum urate levels interaction ( 34046847 )
Entrez ID	51167
HPRD ID	12218
Ensembl ID	ENSG00000065615
Uniprot IDs	Q7L1T6
PDB IDs	3LF5 6MV1 6MV2
GO Terms Enriched among Interactors ?	Chorion Development MLL3/4 Complex Positive Regulation Of Isotype Switching To IgG Isotypes Regulation Of Isotype Switching To IgG Isotypes Positive Regulation Of DNA Recombination Regulation Of Isotype Switching Positive Regulation Of Immunoglobulin Mediated Immune Response DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Immunoglobulin Production Histone Methyltransferase Complex Positive Regulation Of DNA-templated Transcription Initiation Positive Regulation Of Transcription Initiation By RNA Polymerase II Adipose Tissue Development Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Isotype Switching Endothelial Cell Migration Regulation Of DNA-templated Transcription Initiation Vasculogenesis Regulation Of Immunoglobulin Production Regulation Of Transcription Initiation By RNA Polymerase II Connective Tissue Development Positive Regulation Of B Cell Activation Positive Regulation Of Post-translational Protein Modification Regulation Of B Cell Activation Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Cell Cycle G2/M Phase Transition Nuclear Matrix Signal Transduction By P53 Class Mediator Positive Regulation Of Lymphocyte Mediated Immunity Positive Regulation Of Protein Ubiquitination Positive Regulation Of Adaptive Immune Response Regulation Of DNA Recombination Response To Ionizing Radiation Signal Transduction In Response To DNA Damage Regulation Of DNA-binding Transcription Factor Activity Regulation Of Protein Ubiquitination Regulation Of Production Of Molecular Mediator Of Immune Response Regulation Of Lymphocyte Mediated Immunity Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Adaptive Immune Response DNA Recombination Regulation Of Post-translational Protein Modification Positive Regulation Of Immune Effector Process Positive Regulation Of DNA Metabolic Process