AADAT

Description		aminoadipate aminotransferase
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix
	Molecular Function	Transaminase Activity Kynurenine-oxoglutarate Transaminase Activity Transferase Activity Pyridoxal Phosphate Binding Protein Homodimerization Activity Kynurenine-glyoxylate Transaminase Activity 2-aminoadipate Transaminase Activity Glycine:2-oxoglutarate Aminotransferase Activity Methionine-glyoxylate Transaminase Activity
	Biological Process	2-oxoglutarate Metabolic Process Glutamate Metabolic Process L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Kynurenine Metabolic Process Alpha-amino Acid Metabolic Process
Pathways		Lysine catabolism Tryptophan catabolism
Drugs		Pyridoxal phosphate Glutamic acid
Diseases
GWAS		Adult body size ( 32376654) Alcohol consumption ( 31358974) Free thyroxine concentration ( 25743335) Metabolite levels ( 23823483) Thyroid hormone levels ( 23408906)
Novel Interacting Genes		1 novel interacting genes: STT3B
Interacting Genes
Entrez ID		51166
HPRD ID		12392
Ensembl ID		ENSG00000109576
Uniprot IDs		Q4W5N8 Q8N5Z0
PDB IDs		2QLR 2R2N 2VGZ 2XH1 3DC1 3UE8 4GDY 4GE4 4GE7 4GE9 4GEB 5EFS 5EUN 5TF5 6D0A 6T8P 6T8Q
Enriched GO Terms of Interacting Partners?		Oligosaccharyl Transferase Activity Oligosaccharyltransferase Complex B Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Oligosaccharyltransferase Complex Protein N-linked Glycosylation Via Asparagine Glycoprotein Catabolic Process ERAD Pathway Response To Unfolded Protein Protein N-linked Glycosylation Protein Glycosylation Macromolecule Glycosylation Glycosylation Glycosyltransferase Activity Carbohydrate Derivative Catabolic Process Glycoprotein Biosynthetic Process Response To Endoplasmic Reticulum Stress Glycoprotein Metabolic Process
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