ZDHHC9

Description		zDHHC palmitoyltransferase 9
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GO Annotations	Cellular Component	Golgi Membrane Palmitoyltransferase Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Protein Binding Palmitoyltransferase Activity Transferase Activity Acyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity Ras Palmitoyltransferase Activity
	Biological Process	MAPK Cascade Negative Regulation Of T-helper 1 Type Immune Response Ubiquitin-dependent Protein Catabolic Process Protein Targeting To Membrane Peptidyl-L-cysteine S-palmitoylation Virion Attachment To Host Cell ERAD Pathway Host-mediated Activation Of Viral Process Protein Maturation Positive Regulation Of Pyroptotic Inflammatory Response CGAS/STING Signaling Pathway Positive Regulation Of CGAS/STING Signaling Pathway Pyroptotic Cell Death
Pathways		RAS processing Maturation of spike protein
Drugs
Diseases		Syndromic X-linked mental retardation, including: Turner type (MRXST); Siderius type (MRXSSD) ; Cabezas type (MRXC); Raymond type (MRXSR); Type10 (MRXS10); Type14 (MRXS14); Mental retardation with isolated growth hormone deficiency (MRGH)
GWAS		Refractive error ( 32231278)
Interacting Genes		3 interacting genes: CREB3 HRAS NRAS
Entrez ID		51114
HPRD ID		06759
Ensembl ID		ENSG00000188706
Uniprot IDs		Q9Y397
PDB IDs		8HF3
Enriched GO Terms of Interacting Partners?		GDP Binding G Protein Activity Golgi Membrane Ras Protein Signal Transduction Intracellular Signaling Cassette Positive Regulation Of Deacetylase Activity Endoplasmic Reticulum Membrane GTPase Complex Positive Regulation Of Epithelial Cell Proliferation Golgi Apparatus Phospholipase C Activator Activity MAPK Cascade Small GTPase-mediated Signal Transduction GTPase Activity Regulation Of Cell Population Proliferation Intracellular Signal Transduction Chemotaxis CCR1 Chemokine Receptor Binding Release From Viral Latency Locomotion Oncogene-induced Cell Senescence GTP Binding Regulation Of Epithelial Cell Proliferation T-helper 1 Type Immune Response CAMP Response Element Binding Protein Binding Positive Regulation Of Ruffle Assembly Induction Of Positive Chemotaxis Positive Regulation Of Cell Migration Schwann Cell Development Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Protein Targeting To Membrane Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Positive Chemotaxis Regulation Of Protein Localization To Synapse Cellular Response To Gamma Radiation Defense Response To Protozoan Regulation Of Receptor Localization To Synapse Regulation Of Protein Targeting To Membrane Response To Protozoan Regulation Of Ruffle Assembly Regulation Of Monocyte Chemotaxis Protein-membrane Adaptor Activity Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Integrated Stress Response Signaling Negative Regulation Of Apoptotic Process Fibroblast Proliferation
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