LAP3

Description		leucine aminopeptidase 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Trans-Golgi Network Focal Adhesion Extracellular Exosome
	Molecular Function	Aminopeptidase Activity Carboxypeptidase Activity Protein Binding Peptidase Activity Metalloexopeptidase Activity Hydrolase Activity Manganese Ion Binding Metal Ion Binding Metalloaminopeptidase Activity
	Biological Process	Proteolysis
Pathways
Drugs		Leucine Phosphonic Acid (2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid Zofenoprilat
Diseases
GWAS
Interacting Genes		15 interacting genes: APP BANP CBX3 CBX5 FXR1 LIG4 LINC00632 MAPRE3 OGT PIH1D2 PIK3R3 TAB1 USF1 ZNF76 ZYX
Entrez ID		51056
HPRD ID		07516
Ensembl ID		ENSG00000002549
Uniprot IDs		P28838
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription By Glucose Negative Regulation Of Long-term Synaptic Potentiation Protein Serine/threonine Kinase Binding Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Multicellular Organismal Process Pericentric Heterochromatin Amyloid-beta Complex Growth Cone Lamellipodium Chromatin Organization Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Biosynthetic Process Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Macromolecule Biosynthetic Process Establishment Of Integrated Proviral Latency Positive Regulation Of Neurogenesis Chromosome, Telomeric Region Cellular Response To Nutrient Ribonucleoprotein Complex Binding Nuclear Envelope Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Site Of DNA Damage Heterochromatin Regulation Of Glycolytic Process Regulation Of Neuronal Synaptic Plasticity Acetylcholine Receptor Activator Activity Positive Regulation Of Macromolecule Metabolic Process PTB Domain Binding Regulation Of ATP Metabolic Process Regulation Of Macromolecule Biosynthetic Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Synapse Organization Negative Regulation Of Gene Expression Epigenetic Regulation Of Gene Expression Regulation Of Carbohydrate Catabolic Process Regulation Of Gene Expression Regulation Of Purine Nucleotide Metabolic Process Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import
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