ST8SIA3

Gene Name		ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Integral Component Of Golgi Membrane
	Molecular Function	Alpha-N-acetylneuraminate Alpha-2,8-sialyltransferase Activity Sialic Acid Binding
	Biological Process	Ganglioside Biosynthetic Process Protein Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process N-glycan Processing Glycosphingolipid Biosynthetic Process Glycoprotein Metabolic Process Oligosaccharide Metabolic Process Protein N-linked Glycosylation Via Asparagine Post-translational Protein Modification Cellular Protein Metabolic Process Sialylation
Pathways		Diseases of glycosylation Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Transport to the Golgi and subsequent modification Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MOGS causes MOGS-CDG (CDG-2b) N-Glycan antennae elongation Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein N-glycan antennae elongation in the medial/trans-Golgi Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Post-translational protein modification Defective ALG3 causes ALG3-CDG (CDG-1d) Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Synthesis of substrates in N-glycan biosythesis Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective RFT1 causes RFT1-CDG (CDG-1n) Defective ALG6 causes ALG6-CDG (CDG-1c) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Sialic acid metabolism Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: NCAM1
Entrez ID		51046
HPRD ID		15343
Ensembl ID		ENSG00000177511
Uniprot IDs		O43173 Q59GW3
PDB IDs
Enriched GO Terms of Interacting Partners?
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