ISOC1

Description		isochorismatase domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Peroxisome
	Molecular Function	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Hip circumference ( 28552196) Hip circumference adjusted for BMI ( 28552196) Intraocular pressure ( 29617998) Waist-to-hip ratio adjusted for BMI ( 28552196)
Novel Interacting Genes		1 novel interacting genes: MARK2
Interacting Genes		2 interacting genes: CALCOCO1 CFTR
Entrez ID		51015
HPRD ID		13030
Ensembl ID		ENSG00000066583
Uniprot IDs		Q96CN7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Wnt Signaling Pathway Establishment Or Maintenance Of Cell Polarity Regulating Cell Shape Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Microtubule Bundle Regulation Of Neurofibrillary Tangle Assembly Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Organelle Localization Epithelial Fluid Transport Golgi-associated Vesicle Membrane Cellular Response To Forskolin Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Tau-protein Kinase Activity Regulation Of Inclusion Body Assembly Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Sterol Biosynthetic Process Protein Kinase Activator Activity
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