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TAS2R8

Description taste 2 receptor member 8
Image No pdb structure
GO Annotations Cellular Component
  • Plasma Membrane
  • Membrane
Molecular Function
  • G Protein-coupled Receptor Activity
  • Protein Binding
  • Taste Receptor Activity
  • Bitter Taste Receptor Activity
Biological Process
  • Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste
  • Signal Transduction
  • G Protein-coupled Receptor Signaling Pathway
  • Sensory Perception Of Taste
Pathways
  • G alpha (i) signalling events
  • Class C/3 (Metabotropic glutamate/pheromone receptors)
  • Sensory perception of sweet, bitter, and umami (glutamate) taste
  • Sensory perception of sweet, bitter, and umami (glutamate) taste
Drugs
Diseases
GWAS
Interacting Genes 1 interacting genes: NHERF4
Entrez ID 50836
HPRD ID 16072
Ensembl ID ENSG00000121314
Uniprot IDs Q9NYW2
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Guanylate Cyclase Inhibitor Activity
  • Negative Regulation Of CGMP-mediated Signaling
  • Receptor Guanylyl Cyclase Signaling Pathway
  • Regulation Of CGMP-mediated Signaling
  • Ion Channel Inhibitor Activity
  • Ubiquitin-specific Protease Binding
  • Apical Junction Complex
  • Protein-membrane Adaptor Activity
  • Fluid Transport
  • Water Transport
  • Brush Border
  • Apical Part Of Cell
  • Response To Toxic Substance
  • Protein Localization To Plasma Membrane
  • Protein Localization To Cell Periphery
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