NEUROG3

Gene Name		neurogenin 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Core Promoter Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Double-stranded DNA Binding Transcription Coactivator Activity Chromatin DNA Binding Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Nervous System Development Central Nervous System Development Peripheral Nervous System Development Spinal Cord Development Epithelial Cell Differentiation Forebrain Development Hindbrain Development Endocrine Pancreas Development Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Dendrite Morphogenesis Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Transdifferentiation
Pathways		Regulation of beta-cell development Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: REL TCF12
Entrez ID		50674
HPRD ID		05346
Ensembl ID
Uniprot IDs		Q9Y4Z2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Interleukin-12 Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Immune Response Positive Regulation Of Transcription, DNA-templated NIK/NF-kappaB Signaling Positive Regulation Of Interleukin-12 Production Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process I-kappaB Kinase/NF-kappaB Signaling Regulation Of Interleukin-12 Production Positive Regulation Of Cytokine Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Immune System Process Regulation Of Cytokine Biosynthetic Process Transcription, DNA-templated RNA Biosynthetic Process Cytokine Production
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