CHST11

Description		carbohydrate sulfotransferase 11
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Dermatan 4-sulfotransferase Activity Sulfotransferase Activity Transferase Activity Chondroitin 4-sulfotransferase Activity N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase Activity
	Biological Process	In Utero Embryonic Development Chondrocyte Development Apoptotic Process Transforming Growth Factor Beta Receptor Signaling Pathway Respiratory Gaseous Exchange By Respiratory System Post-embryonic Development Carbohydrate Biosynthetic Process Proteoglycan Biosynthetic Process Embryonic Limb Morphogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Polysaccharide Localization Post-anal Tail Morphogenesis Regulation Of Cell Population Proliferation Embryonic Digit Morphogenesis Negative Regulation Of Apoptotic Process Developmental Growth Embryonic Viscerocranium Morphogenesis Embryonic Skeletal System Morphogenesis Chondroitin Sulfate Proteoglycan Biosynthetic Process Chondroitin Sulfate Proteoglycan Metabolic Process Cartilage Development
Pathways		CS-GAG biosynthesis
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Cannabis dependence ( 21668797) Height ( 31562340) LDL levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429) Logical memory (delayed recall) in normal cognition ( 29274321) Obesity-related traits ( 23251661) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) tricyclic pyrone compound response (IC50) ( 33610756) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		1 interacting genes: YWHAE
Entrez ID		50515
HPRD ID		13055
Ensembl ID		ENSG00000171310
Uniprot IDs		Q9NPF2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Heart Rate By Hormone Regulation Of Heart Rate By Chemical Signal Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Phosphoserine Residue Binding Positive Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Hippo Signaling Membrane Repolarization During Action Potential Calcium Channel Regulator Activity Cell Surface Toll-like Receptor Signaling Pathway Potassium Channel Regulator Activity Protein Localization To Endoplasmic Reticulum Regulation Of Protein Export From Nucleus Hippo Signaling MHC Class II Protein Complex Binding Protein Sequestering Activity Substantia Nigra Development Regulation Of Membrane Repolarization Protein K11-linked Ubiquitination Regulation Of Heart Rate By Cardiac Conduction Membrane Repolarization Membrane Repolarization During Cardiac Muscle Cell Action Potential Negative Regulation Of Toll-like Receptor Signaling Pathway Negative Regulation Of Calcium Ion Transmembrane Transport Regulation Of Toll-like Receptor Signaling Pathway Positive Regulation Of Protein Export From Nucleus Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Hippo Signaling Phosphoprotein Binding Molecular Function Inhibitor Activity Calcium Channel Inhibitor Activity Cardiac Conduction Intracellular Potassium Ion Homeostasis Potassium Ion Homeostasis Protein Phosphatase Inhibitor Activity Negative Regulation Of Calcium Ion Transport Cellular Response To Heat Cell Surface Pattern Recognition Receptor Signaling Pathway Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Pattern Recognition Receptor Signaling Pathway Neural Nucleus Development Positive Regulation Of Nucleocytoplasmic Transport Golgi To Plasma Membrane Transport Negative Regulation Of Cation Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport Hippocampus Development Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Scaffold Protein Binding Negative Regulation Of Monoatomic Ion Transmembrane Transport Signaling Adaptor Activity
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