OXCT1

Description		3-oxoacid CoA-transferase 1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix
	Molecular Function	Succinyl-CoA:3-oxo-acid CoA-transferase Activity CoA-transferase Activity Transferase Activity Identical Protein Binding
	Biological Process	Lipid Metabolic Process Heart Development Response To Nutrient Response To Xenobiotic Stimulus Response To Hormone Response To Activity Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Ketone Catabolic Process Response To Starvation Response To Ethanol Ketone Body Catabolic Process Adipose Tissue Development Ketone Body Metabolic Process
Pathways		Utilization of Ketone Bodies Mitochondrial protein degradation
Drugs		Ethylmercurithiosalicylic acid
Diseases
GWAS		Ketonuria ( 30476138) Ketonuria (mild) ( 30476138) Ketonuria (moderate to severe) ( 30476138)
Interacting Genes		3 interacting genes: LINC01554 OGT PSEN1
Entrez ID		5019
HPRD ID		02001
Ensembl ID		ENSG00000083720
Uniprot IDs		A0A024R040 E9PDW2 P55809
PDB IDs		3DLX
Enriched GO Terms of Interacting Partners?		Regulation Of ATP Metabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Regulation Of Purine Nucleotide Metabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Glycosylation Negative Regulation Of Proteolysis Negative Regulation Of Core Promoter Binding Macromolecule Glycosylation Regulation Of Generation Of Precursor Metabolites And Energy Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Glycosylation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Ubiquitin-dependent Protein Catabolic Process Cajal-Retzius Cell Differentiation Protein Processing Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Protein Catabolic Process At Postsynapse Negative Regulation Of Transcription Regulatory Region DNA Binding Protein O-acetylglucosaminyltransferase Activity Positive Regulation Of L-glutamate Import Across Plasma Membrane Synaptic Vesicle Targeting Astrocyte Activation Involved In Immune Response Sequestering Of Calcium Ion Regulation Of Synapse Organization Protein Maturation Positive Regulation Of Amyloid Fibril Formation Autophagy Aspartic Endopeptidase Activity, Intramembrane Cleaving Growth Factor Receptor Binding Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Small Molecule Metabolic Process Gamma-secretase Complex Carbon Catabolite Regulation Of Transcription Regulation Of L-glutamate Import Across Plasma Membrane Regulation Of Proteolysis Choline Transport Ciliary Rootlet Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Notch Receptor Processing Regulation Of Transcription By Glucose Amyloid-beta Formation
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