OPA1

Gene Name		optic atrophy 1 (autosomal dominant)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Membrane Integral Component Of Membrane Mitochondrial Crista Dendrite
	Molecular Function	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Mitochondrial Genome Maintenance Mitochondrial Fission Neural Tube Closure Apoptotic Process Mitochondrion Organization Inner Mitochondrial Membrane Organization Visual Perception Mitochondrial Fusion Metabolic Process Axon Transport Of Mitochondrion Negative Regulation Of Release Of Cytochrome C From Mitochondria Cellular Senescence Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: APP
Entrez ID		4976
HPRD ID		05596
Ensembl ID		ENSG00000198836
Uniprot IDs		E5KLJ5 E5KLJ6 E5KLJ7 E5KLJ9 E5KLK0 E5KLK1 E5KLK2 O60313
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth Regulation Of Synapse Structure Or Activity Feeding Behavior Regulation Of Multicellular Organism Growth RNA 3'-end Processing Cholesterol Metabolic Process Adult Locomotory Behavior Positive Regulation Of Mitotic Cell Cycle Regulation Of Receptor Activity Cell Recognition
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