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COA5
Description
cytochrome c oxidase assembly factor 5
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Inner Membrane
Molecular Function
Protein Binding
Biological Process
Leukocyte Differentiation
Mitochondrial Cytochrome C Oxidase Assembly
Multicellular Organism Growth
Spleen Development
Thymus Development
Pathways
Complex IV assembly
Drugs
Diseases
Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Interacting Genes
5 interacting genes:
APP
CYSRT1
KRT31
KRTAP1-3
TCF4
Entrez ID
493753
HPRD ID
17563
Ensembl ID
ENSG00000183513
Uniprot IDs
Q86WW8
PDB IDs
Enriched GO Terms of Interacting Partners
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Acetylcholine Receptor Activator Activity
Amyloid-beta Complex
PTB Domain Binding
Growth Cone Lamellipodium
Collateral Sprouting In Absence Of Injury
Regulation Of Protein Import
Regulation Of Response To Calcium Ion
Amylin Binding
Endosome To Plasma Membrane Transport Vesicle
Positive Regulation Of Toll Signaling Pathway
Positive Regulation Of Endothelin Production
Positive Regulation Of Neuron Differentiation
Growth Cone Filopodium
Lipoprotein Particle
Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Protein Import
Microglia Development
Positive Regulation Of G Protein-coupled Receptor Internalization
Epidermis Development
Intermediate Filament
Structural Constituent Of Skin Epidermis
Keratin Filament
Beta-catenin-TCF7L2 Complex
Response To Norepinephrine
Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Intermediate-density Lipoprotein Particle
Axon Midline Choice Point Recognition
Regulation Of Neuron Differentiation
Positive Regulation Of Amyloid Fibril Formation
Cellular Response To Norepinephrine Stimulus
Growth Factor Receptor Binding
Main Axon
Astrocyte Activation Involved In Immune Response
Low-density Lipoprotein Particle Mediated Signaling
TFIIB-class Transcription Factor Binding
Regulation Of Spontaneous Synaptic Transmission
NMDA Selective Glutamate Receptor Signaling Pathway
Regulation Of Synapse Structure Or Activity
Regulation Of Toll Signaling Pathway
Axon Choice Point Recognition
Heparan Sulfate Binding
Signaling Receptor Activator Activity
Peptidase Activator Activity
Cellular Response To Manganese Ion
Antifungal Humoral Response
Nuclear Envelope Lumen
Negative Regulation Of Blood Circulation
Regulation Of Superoxide Anion Generation
Collateral Sprouting
Heparan Sulfate Proteoglycan Binding
Tagcloud
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