ATP2B3

Description		ATPase plasma membrane Ca2+ transporting 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Presynaptic Membrane Cell Projection Intracellular Membrane-bounded Organelle Synapse Parallel Fiber To Purkinje Cell Synapse Glutamatergic Synapse GABA-ergic Synapse Extracellular Vesicle Parallel Fiber
	Molecular Function	Nucleotide Binding P-type Calcium Transporter Activity Protein Binding Calmodulin Binding ATP Binding Calcium Ion Transmembrane Transporter Activity ATP Hydrolysis Activity Metal Ion Binding P-type Calcium Transporter Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Ion Concentration
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Cytosolic Calcium Ion Concentration Calcium Ion Transmembrane Transport Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Cardiac Conduction Calcium Ion Export Across Plasma Membrane
Pathways		Reduction of cytosolic Ca++ levels Ion homeostasis Ion transport by P-type ATPases
Drugs		Ritodrine Halothane Desflurane Sevoflurane
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: DYNC1H1
Interacting Genes		1 interacting genes: HTR2C
Entrez ID		492
HPRD ID		02057
Ensembl ID		ENSG00000067842
Uniprot IDs		A0A994J5M1 Q16720
PDB IDs
Enriched GO Terms of Interacting Partners?		Gq/11-coupled Serotonin Receptor Activity Positive Regulation Of Phosphatidylinositol Biosynthetic Process 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine Binding G Protein-coupled Serotonin Receptor Complex Regulation Of Corticotropin-releasing Hormone Secretion Positive Regulation Of Spindle Assembly Regulation Of Metaphase Plate Congression P-body Assembly Minus-end-directed Microtubule Motor Activity G Protein-coupled Serotonin Receptor Activity Serotonin Binding Phospholipase C-activating Serotonin Receptor Signaling Pathway Serotonin Receptor Activity Positive Regulation Of Phospholipid Biosynthetic Process Serotonin Receptor Signaling Pathway Regulation Of Phospholipid Biosynthetic Process Neurotransmitter Receptor Activity Retrograde Axonal Transport G Protein-coupled Serotonin Receptor Signaling Pathway Cytoplasmic Dynein Complex Regulation Of Appetite Nucleus Localization Stress Granule Assembly Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding Dynein Complex Regulation Of Spindle Assembly Nuclear Migration Behavioral Fear Response Regulation Of Phospholipid Metabolic Process Behavioral Defense Response CGMP-mediated Signaling Fear Response Regulation Of Mitotic Spindle Organization Establishment Of Spindle Localization Cytoplasmic Microtubule Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Calcium-mediated Signaling G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Negative Regulation Of Sequestering Of Calcium Ion Axon Cytoplasm Axonal Transport Spindle Localization Cytoplasmic Microtubule Organization Positive Regulation Of Fat Cell Differentiation Multicellular Organismal Response To Stress Regulation Of Transport Filopodium Axo-dendritic Transport Feeding Behavior
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