NPY2R

Gene Name		neuropeptide Y receptor Y2
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Nonmotile Primary Cilium
	Molecular Function	Peptide YY Receptor Activity Receptor Activity Neuropeptide Y Receptor Activity Calcium Channel Regulator Activity Protein Binding
	Biological Process	Behavioral Fear Response Positive Regulation Of Peptide Secretion Outflow Tract Morphogenesis Cardiac Left Ventricle Morphogenesis Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Nitric Oxide Mediated Signal Transduction Locomotory Behavior Negative Regulation Of CAMP Biosynthetic Process Negative Regulation Of Neurological System Process Positive Regulation Of Dopamine Secretion Positive Regulation Of Cell Adhesion Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Secretion Negative Regulation Of Secretion Regulation Of Sensory Perception Of Pain Negative Regulation Of Synaptic Transmission, Glutamatergic Negative Regulation Of Excitatory Postsynaptic Membrane Potential Negative Regulation Of Feeding Behavior
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: NPY PYY RGS12
Entrez ID		4887
HPRD ID		01216
Ensembl ID		ENSG00000185149
Uniprot IDs		P49146
PDB IDs		2IK3
Enriched GO Terms of Interacting Partners?		Regulation Of Appetite Neuropeptide Signaling Pathway Feeding Behavior Digestion Positive Regulation Of Appetite Response To Nutrient Levels Response To Extracellular Stimulus Adult Feeding Behavior Behavior Regulation Of Response To Food Cell Proliferation Eating Behavior Cell-cell Signaling G-protein Coupled Receptor Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction
Tagcloud ?		adaptations anticonvulsive bdnf conducting decades differing ecs ect egr1 electroconvulsive fos inverse neuritin neuropeptides npy1r npy5r nrn points psd95 quantities seizures snap29 syn synapsin synaptotagmin syt transitory underline