NPY2R

Name	neuropeptide Y receptor Y2
Structure
Interactors	4 interactors: NPY PYY RGS12 TRARG1
GO Annotations	Cellular Component	Plasma Membrane Cilium Membrane Non-motile Cilium Presynapse Glutamatergic Synapse
	Molecular Function	Peptide YY Receptor Activity G Protein-coupled Receptor Activity Neuropeptide Y Receptor Activity Calcium Channel Regulator Activity Protein Binding Signaling Receptor Activity
	Biological Process	Behavioral Fear Response Positive Regulation Of Peptide Secretion Outflow Tract Morphogenesis Cardiac Left Ventricle Morphogenesis Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Nitric Oxide Mediated Signal Transduction Locomotory Behavior Positive Regulation Of Cell-substrate Adhesion Negative Regulation Of Nervous System Process Positive Regulation Of Dopamine Secretion Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Negative Regulation Of Synaptic Transmission Negative Regulation Of Secretion Negative Regulation Of Synaptic Transmission, Glutamatergic Negative Regulation Of Excitatory Postsynaptic Potential Synaptic Signaling Via Neuropeptide Negative Regulation Of CAMP/PKA Signal Transduction Negative Regulation Of Feeding Behavior
Pathways	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs	Cysteamine Peptide YY (3-36) Obinepitide
GWAS	Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678 ) Premature menopause in childhood cancer survivors ( 29432556 )
Entrez ID	4887
HPRD ID	01216
Ensembl ID	ENSG00000185149
Uniprot IDs	P49146
PDB IDs	7X9B 7YON 7YOO 8K6N
GO Terms Enriched among Interactors ?	Neuropeptide Y Receptor Binding Intestinal Epithelial Cell Differentiation Neuropeptide Hormone Activity G Protein-coupled Receptor Binding Feeding Behavior Neuropeptide Signaling Pathway Short-day Photoperiodism Hormone Activity G Protein-coupled Receptor Signaling Pathway Regulation Of Nerve Growth Factor Production Positive Regulation Of Eating Behavior Positive Regulation Of Response To Food Positive Regulation Of Appetite Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Positive Regulation Of Dopamine Metabolic Process Glucose Import In Response To Insulin Stimulus Regulation Of Eating Behavior Synaptic Signaling Via Neuropeptide Monocyte Activation Antifungal Humoral Response Adult Feeding Behavior Positive Regulation Of Feeding Behavior Vesicle Fusion To Plasma Membrane Negative Regulation Of Acute Inflammatory Response Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Epithelial Cell Differentiation Endosome To Plasma Membrane Protein Transport Response To Yeast Regulation Of Acute Inflammatory Response To Antigenic Stimulus Regulation Of Response To Food D-glucose Import Regulation Of Dopamine Metabolic Process Neuronal Dense Core Vesicle Regulation Of Appetite Regulation Of Feeding Behavior GTPase Regulator Activity Photoperiodism D-glucose Transmembrane Transport Positive Regulation Of Behavior Negative Regulation Of Inflammatory Response To Antigenic Stimulus Hexose Transmembrane Transport Regulation Of Response To Nutrient Levels Terminal Bouton Perinuclear Region Of Cytoplasm Positive Regulation Of Nitric Oxide Metabolic Process Calcium Channel Regulator Activity Central Nervous System Neuron Development Negative Regulation Of Blood Pressure Regulation Of Acute Inflammatory Response Carbohydrate Transmembrane Transport