NMBR

Description		neuromedin B receptor
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GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Bombesin Receptor Activity Neuropeptide Receptor Activity G Protein-coupled Peptide Receptor Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Bombesin Receptor Signaling Pathway Negative Regulation Of Interleukin-6 Production Positive Regulation Of Interferon-alpha Production Positive Regulation Of Osteoclast Proliferation Antiviral Innate Immune Response Sneeze Reflex Positive Regulation Of Respiratory Gaseous Exchange
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Birth weight ( 31043758) Body size at age 10 ( 32376654) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Retinal vascular caliber ( 21060863) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
Interacting Genes		1 interacting genes: NMB
Entrez ID		4829
HPRD ID		01211
Ensembl ID		ENSG00000135577
Uniprot IDs		P28336
PDB IDs		8H0P
Enriched GO Terms of Interacting Partners?		Sensory Perception Of Itch Sneeze Reflex Positive Regulation Of Testosterone Secretion Neuromedin B Receptor Binding Positive Regulation Of Osteoclast Proliferation Leydig Cell Proliferation Positive Regulation Of Respiratory Gaseous Exchange Reflex Positive Regulation Of Interferon-alpha Production Arachidonate Secretion Regulation Of Respiratory Gaseous Exchange Neuropeptide Hormone Activity Negative Regulation Of Interleukin-6 Production Long-chain Fatty Acid Transport Negative Regulation Of Hormone Secretion Antiviral Innate Immune Response Positive Regulation Of Lipid Transport Fatty Acid Transport Positive Regulation Of Type I Interferon Production Neuropeptide Signaling Pathway Hormone Activity Regulation Of Type I Interferon Production Monocarboxylic Acid Transport Positive Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Secretion By Cell Regulation Of Lipid Transport Positive Regulation Of Hormone Secretion Regulation Of Interleukin-6 Production Negative Regulation Of Secretion Positive Regulation Of Leukocyte Proliferation Regulation Of Hormone Secretion Carboxylic Acid Transport Organic Acid Transport Regulation Of Leukocyte Proliferation Defense Response To Virus
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