NKX2-2

Gene Name		NK2 homeobox 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm
	Molecular Function	Core Promoter Proximal Region DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Transcription Factor Binding Sequence-specific DNA Binding
	Biological Process	Type B Pancreatic Cell Development Pancreatic A Cell Fate Commitment Type B Pancreatic Cell Fate Commitment Pancreatic PP Cell Fate Commitment Transcription, DNA-templated Smoothened Signaling Pathway Brain Development Response To Glucose Oligodendrocyte Development Spinal Cord Motor Neuron Differentiation Spinal Cord Oligodendrocyte Cell Fate Specification Optic Nerve Development Endocrine Pancreas Development Response To Progesterone Negative Regulation Of Neuron Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Digestive Tract Development Neuron Fate Specification Astrocyte Differentiation Positive Regulation Of Oligodendrocyte Differentiation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Ventral Spinal Cord Interneuron Fate Determination
Pathways		Regulation of beta-cell development Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells Regulation of gene expression in beta cells
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: OLIG2
Entrez ID		4821
HPRD ID		05213
Ensembl ID		ENSG00000125820
Uniprot IDs		O95096
PDB IDs
Enriched GO Terms of Interacting Partners?		Spinal Cord Oligodendrocyte Cell Fate Specification Oligodendrocyte Cell Fate Specification Thalamus Development Positive Regulation Of Oligodendrocyte Differentiation Glial Cell Fate Commitment Positive Regulation Of Glial Cell Differentiation Regulation Of Oligodendrocyte Differentiation Spinal Cord Motor Neuron Differentiation Positive Regulation Of Gliogenesis Ventral Spinal Cord Development Cell Differentiation In Spinal Cord Regulation Of Glial Cell Differentiation Oligodendrocyte Differentiation Neuron Fate Commitment Diencephalon Development Cell Fate Specification Regulation Of Gliogenesis Spinal Cord Development Myelination Axon Ensheathment Glial Cell Differentiation Negative Regulation Of Neuron Differentiation Central Nervous System Neuron Differentiation Gliogenesis Negative Regulation Of Neurogenesis Cell Fate Commitment
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