TONSL

Description		tonsoku like, DNA repair protein
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm DNA Replication Factor A Complex Chromosome Cytoplasm Nuclear Body FACT Complex Site Of Double-strand Break MCM Complex Nuclear Replication Fork
	Molecular Function	Protein Binding Histone Binding Histone Reader Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Repair Chromatin Organization DNA Damage Response Replication Fork Processing Protein Localization To Chromatin
Pathways
Drugs
Diseases
GWAS		Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Serum alkaline phosphatase levels ( 33547301)
Novel Interacting Genes		1 novel interacting genes: GPAA1
Interacting Genes		5 interacting genes: CFTR EWSR1 GSK3B MYC PEX14
Entrez ID		4796
HPRD ID		05180
Ensembl ID		ENSG00000160949
Uniprot IDs		Q96HA7
PDB IDs		5JA4
Enriched GO Terms of Interacting Partners?		Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Regulation Of Microtubule Anchoring At Centrosome Regulation Of Protein Binding Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Acinar Cell Proliferation Positive Regulation Of Acinar Cell Proliferation SCF Ubiquitin Ligase Complex Binding Peroxisome Transport Along Microtubule Positive Regulation Of Anion Channel Activity Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity Myc-Max Complex Regulation Of Acinar Cell Proliferation Cellular Response To Stress Positive Regulation Of Monoatomic Anion Transport NK T Cell Proliferation Protein-containing Complex Disassembly Peroxisomal Importomer Complex GPI-anchor Transamidase Activity Positive Regulation Of Enamel Mineralization Mitotic Cell Cycle Phase Transition Negative Regulation Of TORC2 Signaling Negative Regulation Of Dopaminergic Neuron Differentiation Regulation Of Glycogen (starch) Synthase Activity Cell Cycle Phase Transition Positive Regulation Of B Cell Apoptotic Process Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Matrix, Docking Protein-containing Complex Transepithelial Water Transport Beta-arrestin-dependent Dopamine Receptor Signaling Pathway GPI-anchor Transamidase Complex GPI Anchored Protein Biosynthesis Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Cellular Response To Oxygen-containing Compound Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Positive Regulation Of Protein Localization To Cilium Cellular Response To Interleukin-3 Positive Regulation Of Protein Localization To Centrosome Negative Regulation Of DNA-templated Transcription Initiation Negative Regulation Of Transcription Initiation By RNA Polymerase II
Tagcloud ?