TONSL

Gene Name		tonsoku-like, DNA repair protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm DNA Replication Factor A Complex Cytoplasm FACT Complex MCM Complex Nuclear Replication Fork
	Molecular Function	Transcription Corepressor Activity Protein Binding Histone Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Replication Fork Processing Cytoplasmic Sequestering Of Transcription Factor Negative Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: EWSR1 GSK3B MYC
Entrez ID		4796
HPRD ID		05180
Ensembl ID		ENSG00000160949
Uniprot IDs		Q96HA7
PDB IDs
Enriched GO Terms of Interacting Partners?		Canonical Wnt Signaling Pathway Energy Reserve Metabolic Process Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Negative Regulation Of MAPK Cascade Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development Fibroblast Apoptotic Process Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Wnt Signaling Pathway Hypermethylation Of CpG Island Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Positive Regulation Of Proteolysis Energy Derivation By Oxidation Of Organic Compounds Cellular Response To Interleukin-3 Negative Regulation Of Monocyte Differentiation Regulation Of Neuron Maturation Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Cell Proliferation Involved In Kidney Development Negative Regulation Of Phosphorylation Protein Localization To Microtubule Negative Regulation Of Intracellular Signal Transduction Generation Of Precursor Metabolites And Energy Negative Regulation Of Dendrite Morphogenesis Negative Regulation Of NFAT Protein Import Into Nucleus ER Overload Response Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Muscle Hypertrophy Regulation Of Glycogen (starch) Synthase Activity Response To Drug Regulation Of Monocyte Differentiation Positive Regulation Of Protein Export From Nucleus Cellular Response To Growth Factor Stimulus Positive Regulation Of Apoptotic Process Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Programmed Cell Death Response To Growth Factor Positive Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Dendrite Development Positive Regulation Of Cell Death Regulation Of MAPK Cascade Regulation Of Proteolysis Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Regulation Of DNA Methylation Myoblast Fusion Protein Localization To Cytoskeleton Negative Regulation Of Cell Differentiation Oxygen Transport
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