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NDUFA8
Gene Name
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Respiratory Chain Complex I
Mitochondrial Intermembrane Space
Molecular Function
NADH Dehydrogenase (ubiquinone) Activity
Protein Complex Binding
Biological Process
Mitochondrial Electron Transport, NADH To Ubiquinone
Respiratory Electron Transport Chain
Cellular Metabolic Process
Small Molecule Metabolic Process
Pathways
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
Respiratory electron transport
The citric acid (TCA) cycle and respiratory electron transport
Drugs
NADH
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-protein Interactions
1 interactors:
KDM1A
Entrez ID
4702
HPRD ID
04525
Ensembl ID
ENSG00000119421
Uniprot IDs
F5H7V7
P51970
PDB IDs
Enriched GO Terms of Interacting Partners
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Regulation Of Primitive Erythrocyte Differentiation
Negative Regulation Of Histone H3-K4 Methylation
Histone H3-K9 Demethylation
Histone H3-K4 Demethylation
Positive Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Hormone Biosynthetic Process
Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Negative Regulation Of Histone H3-K9 Methylation
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Granulocyte Differentiation
Regulation Of Megakaryocyte Differentiation
Negative Regulation Of Histone Methylation
Positive Regulation Of Erythrocyte Differentiation
Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Regulation Of Histone H3-K4 Methylation
Negative Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Hormone Biosynthetic Process
Regulation Of Hematopoietic Progenitor Cell Differentiation
Histone Lysine Demethylation
Regulation Of Hormone Metabolic Process
Histone Demethylation
Regulation Of Erythrocyte Differentiation
Protein Demethylation
Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of DNA Binding
Regulation Of Histone Methylation
Positive Regulation Of Neural Precursor Cell Proliferation
Pituitary Gland Development
Negative Regulation Of Protein Binding
Demethylation
Positive Regulation Of Stem Cell Proliferation
Positive Regulation Of Myeloid Cell Differentiation
Regulation Of DNA Binding
Negative Regulation Of Chromosome Organization
Diencephalon Development
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Binding
Regulation Of Neural Precursor Cell Proliferation
Regulation Of Stem Cell Proliferation
Myeloid Leukocyte Differentiation
Regulation Of Embryonic Development
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Histone Modification
Regulation Of Response To DNA Damage Stimulus
Regulation Of Protein Binding
Regulation Of Intrinsic Apoptotic Signaling Pathway
Muscle Cell Development
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