NDUFA8

Description		NADH:ubiquinone oxidoreductase subunit A8
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Membrane Respiratory Chain Complex I
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity Protein-containing Complex Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport
Pathways		Respiratory electron transport Complex I biogenesis
Drugs		NADH
Diseases
GWAS		Brain asymmetrical skew (vertical) ( 33836062) Malaria ( 31844061) Obesity-related traits ( 23251661)
Interacting Genes		3 interacting genes: KDM1A TRIM55 TRIM63
Entrez ID		4702
HPRD ID		04525
Ensembl ID		ENSG00000119421
Uniprot IDs		B7Z768 P51970
PDB IDs		5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?		Protein Modification Process Response To Fungicide MRF Binding Histone H3K4 Demethylase Activity Guanine Metabolic Process Protein Demethylase Activity Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Ubiquitin Protein Ligase Activity Microtubule Diapedesis Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Skeletal Muscle Atrophy Skeletal Muscle Adaptation Striated Muscle Atrophy Muscle Atrophy Histone H3K9 Demethylase Activity Purine Nucleobase Metabolic Process Positive Regulation Of Cell Size Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Nuclear Androgen Receptor Binding Positive Regulation Of Neuroblast Proliferation Telomeric DNA Binding Histone Demethylase Activity Histone Methyltransferase Complex Regulation Of Chromatin Organization Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Cellular Response To Gamma Radiation DNA Repair-dependent Chromatin Remodeling Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator DNA Repair Complex Protein Metabolic Process Leukocyte Migration Involved In Inflammatory Response Macrophage Migration Protein Ubiquitination Innate Immune Response Protein Modification By Small Protein Conjugation M Band Negative Regulation Of Glycolytic Process Titin Binding Contractile Muscle Fiber Negative Regulation Of ATP Metabolic Process Neuron Maturation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Defense Response To Symbiont Defense Response To Other Organism Regulation Of Androgen Receptor Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
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