COXFA4

Name	cytochrome c oxidase associated subunit FA4
Structure
Novel Interactors	1 novel interactors: FBLN5
Interactors	2 interactors: APP PARK7
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Membrane Respiratory Chain Complex I Respiratory Chain Complex IV
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity Protein-containing Complex Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Mitochondrial Electron Transport, Cytochrome C To Oxygen Cellular Respiration Proton Transmembrane Transport
Pathways	TP53 Regulates Metabolic Genes Respiratory electron transport Cytoprotection by HMOX1 Complex IV assembly
Drugs	NADH
GWAS	No GWAS studies recorded
Entrez ID	4697
HPRD ID	04831
Ensembl ID	ENSG00000189043
Uniprot IDs	O00483
PDB IDs	5Z62
GO Terms Enriched among Interactors ?	Regulation Of Reactive Oxygen Species Metabolic Process Signaling Receptor Activator Activity Regulation Of Superoxide Metabolic Process Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Amyloid-beta Complex Growth Cone Lamellipodium Adult Locomotory Behavior Regulation Of Response To Calcium Ion Cell Body Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress Protein Homodimerization Activity Peptidase Inhibitor Activity Regulation Of Cellular Response To Stress Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Generation Of Precursor Metabolites And Energy Intramembranous Bone Growth Glyoxal Catabolic Process L-dopa Decarboxylase Activator Activity Guanine Deglycation Protein Deglycase Activity Glyoxalase (glycolic Acid-forming) Activity Glycolate Biosynthetic Process Guanine Deglycation, Methylglyoxal Removal Guanine Deglycation, Glyoxal Removal Detoxification Of Mercury Ion Negative Regulation Of Death-inducing Signaling Complex Assembly Cellular Response To Glyoxal Glyoxal Metabolic Process Positive Regulation Of L-dopa Biosynthetic Process Tyrosine 3-monooxygenase Activator Activity Integrin Binding Positive Regulation Of Apoptotic Signaling Pathway Adult Behavior Regulation Of Protein Localization To Nucleus Positive Regulation Of Small Molecule Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Acetylcholine Receptor Activator Activity Membrane Raft PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Inflammatory Response Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Intrinsic Apoptotic Signaling Pathway Endosome To Plasma Membrane Transport Vesicle Negative Regulation Of Protein Localization Positive Regulation Of Endothelin Production Growth Cone Filopodium