MYO1E

Name	myosin IE
Structure	No pdb structure
Novel Interactors	1 novel interactors: SMAD6
Interactors	7 interactors: ACTB CLIC6 CREBBP LTB4R2 PDE4B RIPK4 SRPK2
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Microvillus Brush Border Adherens Junction Actin Cytoskeleton Myosin Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Clathrin-coated Endocytic Vesicle Extracellular Exosome Anchoring Junction
	Molecular Function	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding Lipid Binding ATP Hydrolysis Activity Phosphatidylinositol Binding Actin Filament Binding
	Biological Process	Vasculogenesis In Utero Embryonic Development Kidney Development Glomerular Filtration Endocytosis Actin Filament Organization Hemopoiesis Glomerulus Development Glomerular Basement Membrane Development Post-embryonic Hemopoiesis Platelet-derived Growth Factor Receptor Signaling Pathway Podocyte Development
Drugs	Imidazole
GWAS	Adult body size ( 32376654 ) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444 ) Metabolite levels ( 22916037 ) Plateletcrit ( 32888494 ) Pulse pressure ( 30224653 ) Serum metabolite levels (CMS) ( 31636271 ) Social communication problems ( 24047820 )
Entrez ID	4643
HPRD ID	03281
Ensembl ID	ENSG00000157483
Uniprot IDs	Q12965 Q4KMR3
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Positive Regulation Of Double-strand Break Repair Positive Regulation Of DNA Recombination Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Chromatin Regulation Of Double-strand Break Repair Via Homologous Recombination Tau Protein Binding Multicellular Organismal-level Homeostasis Regulation Of Norepinephrine Uptake Positive Regulation Of Norepinephrine Uptake Transporter Regulator Activity Cellular Response To Cytochalasin B Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Histone H3K27 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Zygotic Specification Of Dorsal/ventral Axis Type I Activin Receptor Binding Negative Regulation Of Relaxation Of Cardiac Muscle D2 Dopamine Receptor Binding D4 Dopamine Receptor Binding D3 Dopamine Receptor Binding Leukotriene B4 Receptor Activity Leukotriene Receptor Activity Regulation Of DNA Recombination Regulation Of Double-strand Break Repair Positive Regulation Of DNA Repair Regulation Of Transepithelial Transport Protein Localization To Adherens Junction Dense Body MRF Binding Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Nuclear Speck Organization Leukotriene Signaling Pathway Chromatin Remodeling Anatomical Structure Morphogenesis Positive Regulation Of Macromolecule Biosynthetic Process Morphogenesis Of A Polarized Epithelium Activin Receptor Binding Regulation Of Relaxation Of Cardiac Muscle Keratinocyte Migration Structural Constituent Of Postsynaptic Actin Cytoskeleton Negative Regulation Of Relaxation Of Muscle Positive Regulation Of Biosynthetic Process