MYL3

Description		myosin light chain 3
Image
GO Annotations	Cellular Component	Cytosol Muscle Myosin Complex Myosin Complex Myosin II Complex Sarcomere A Band I Band
	Molecular Function	Cytoskeletal Motor Activity Actin Monomer Binding Calcium Ion Binding Structural Constituent Of Muscle Myosin II Heavy Chain Binding
	Biological Process	Regulation Of The Force Of Heart Contraction Muscle Contraction Regulation Of Striated Muscle Contraction Skeletal Muscle Tissue Development Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction
Pathways		Striated Muscle Contraction
Drugs
Diseases		Hypertrophic cardiomyopathy (HCM)
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Metabolite levels ( 23823483) Microalbuminuria ( 26631737 31511532) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31511532 31630189)
Interacting Genes		4 interacting genes: ATG101 CASP3 FTH1 UBC
Entrez ID		4634
HPRD ID		01183
Ensembl ID		ENSG00000160808
Uniprot IDs		P08590
PDB IDs		5TBY 8ACT 8G4L
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Population Proliferation Anterior Neural Tube Closure Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Cellular Response To Staurosporine Phospholipase A2 Activator Activity Ferritin Complex Ferroxidase Activity Iron Ion Sequestering Activity Luteolysis Glial Cell Apoptotic Process Positive Regulation Of Pyroptotic Inflammatory Response Response To Anesthetic Regulation Of Synaptic Vesicle Cycle Response To Cobalt Ion Interleukin-18-mediated Signaling Pathway Protein-containing Complex Binding Death-inducing Signaling Complex Regulation Of Cell Population Proliferation Fibroblast Apoptotic Process Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Regulation Of Autophagy Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Activated T Cell Proliferation Regulation Of Ferroptosis Autolysosome Ferric Iron Binding Negative Regulation Of Ferroptosis Protein Tag Activity Atg1/ULK1 Kinase Complex Negative Regulation Of B Cell Proliferation Death Receptor Binding Positive Regulation Of Amyloid-beta Formation Aspartic-type Endopeptidase Activity Axonal Fasciculation Neuron Projection Fasciculation Protein Poly-ADP-ribosylation Catabolic Process Ferrous Iron Binding Platelet Formation Execution Phase Of Apoptosis Positive Regulation Of Amyloid Precursor Protein Catabolic Process Response To X-ray
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