MT-ND6

Name	NADH dehydrogenase subunit 6
Structure
Interactors	1 interactors: SHANK3
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex I
	Molecular Function	NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Mitochondrial Respiratory Chain Complex I Assembly Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport
Pathways	Mitochondrial translation termination Respiratory electron transport Complex I biogenesis Mitochondrial protein degradation
Drugs	NADH
Diseases	Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS	No GWAS studies recorded
Entrez ID	4541
HPRD ID	08956
Ensembl ID	ENSG00000198695
Uniprot IDs	P03923 U5Z977
PDB IDs	5XTC 5XTD
GO Terms Enriched among Interactors ?	Guanylate Kinase-associated Protein Clustering Vocal Learning Negative Regulation Of Cell Volume Neuron Spine Postsynaptic Density Assembly Positive Regulation Of Long-term Neuronal Synaptic Plasticity AMPA Glutamate Receptor Clustering Synaptic Receptor Adaptor Activity Regulation Of Synapse Structural Plasticity Positive Regulation Of Synapse Structural Plasticity NMDA Glutamate Receptor Clustering Observational Learning Striatal Medium Spiny Neuron Differentiation Positive Regulation Of Glutamate Receptor Signaling Pathway GABAergic Neuron Differentiation Regulation Of Glutamate Receptor Signaling Pathway Postsynaptic Specialization Assembly Neurotransmitter-gated Ion Channel Clustering Auditory Behavior Regulation Of Long-term Synaptic Depression Mechanosensory Behavior Dendritic Spine Morphogenesis Postsynaptic Density Organization Brain Morphogenesis Vocalization Behavior Positive Regulation Of Long-term Synaptic Potentiation Postsynaptic Specialization Organization Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Excitatory Postsynaptic Potential Ionotropic Glutamate Receptor Binding Positive Regulation Of Synaptic Transmission, Glutamatergic Dendritic Spine Organization Forebrain Neuron Differentiation Negative Regulation Of Actin Filament Bundle Assembly Cell Volume Homeostasis Positive Regulation Of Dendritic Spine Development Regulation Of Long-term Synaptic Potentiation Neuron Projection Organization Regulation Of Dendritic Spine Morphogenesis Postsynapse Organization Receptor Clustering Neuromuscular Process Controlling Balance Modulation Of Excitatory Postsynaptic Potential Social Behavior Regulation Of Dendritic Spine Development Ciliary Membrane Regulation Of Neuronal Synaptic Plasticity Scaffold Protein Binding Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Cell Size