MTF1

Description		metal regulatory transcription factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Histone Acetyltransferase Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Response To Oxidative Stress Central Nervous System Development Response To Metal Ion Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Response To Cadmium Ion Cellular Response To Zinc Ion Cartilage Homeostasis
Pathways		PPARA activates gene expression Activation of gene expression by SREBF (SREBP) MTF1 activates gene expression MTF1 activates gene expression
Drugs		Silver
Diseases
GWAS		Eyebrow thickness ( 26926045) Hypothyroidism ( 22493691 27182965) Platelet distribution width ( 32888494) Pulse pressure ( 27841878) Rheumatoid arthritis ( 24390342 30423114) Systemic lupus erythematosus ( 33536424)
Novel Interacting Genes		1 novel interacting genes: PABPC4
Interacting Genes		2 interacting genes: AP1M1 LATS1
Entrez ID		4520
HPRD ID		02546
Ensembl ID		ENSG00000188786
Uniprot IDs		Q14872
PDB IDs
Enriched GO Terms of Interacting Partners?		Poly(C) RNA Binding Inner Cell Mass Cell Fate Commitment Inner Cell Mass Cellular Morphogenesis
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