MN1

Description		MN1 proto-oncogene, transcriptional regulator
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus
	Molecular Function	Protein Binding
	Biological Process	Intramembranous Ossification Regulation Of DNA-templated Transcription Negative Regulation Of Osteoblast Proliferation Positive Regulation Of Vitamin D Receptor Signaling Pathway Regulation Of Cell Cycle G1/S Phase Transition
Pathways
Drugs
Diseases
GWAS		Age-related cataracts ( 25352737) Blood pressure (smoking interaction) ( 25189868) FEV1 ( 30804560) Lung function (FEV1) ( 26635082 28166213) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 26635082) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Mild obesity-related type 2 diabetes ( 34737425) Mitral valve prolapse ( 26301497) Moderate or severe prolonged lymphopenia in dimethyl fumarate-treated relapsing-remitting multiple sclerosis ( 31749835) Peak expiratory flow ( 30804560) Platelet count ( 27863252 32888494) Platelet reactivity in response to clopidogrel treatment ( 32472697) Plateletcrit ( 27863252 32888494) Pulse pressure ( 30224653) Red blood cell count ( 32888494) Refractive error ( 32231278) Resting heart rate ( 27798624) Urate levels in obese individuals ( 25811787) White matter hyperintensity volume ( 33293549) White matter hyperintensity volume (adjusted for hypertension) ( 33293549) White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
Novel Interacting Genes		1 novel interacting genes: CHEK2
Interacting Genes		2 interacting genes: EP300 NCOA3
Entrez ID		4330
HPRD ID		08862
Ensembl ID		ENSG00000169184
Uniprot IDs		Q10571
PDB IDs
Enriched GO Terms of Interacting Partners?		Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Histone Acetyltransferase Activity Protein-lysine-acetyltransferase Activity Nuclear Receptor Binding Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Autophagosome Assembly Cellular Response To Oxygen-containing Compound Peptidyl-lysine Propionylation Swimming Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Autophagosome Organization Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity Signal Transduction By P53 Class Mediator Transcription Coregulator Activity Regulation Of Signal Transduction By P53 Class Mediator Acyltransferase Activity Vacuole Organization Histone H2B Acetyltransferase Activity Acetylation-dependent Protein Binding Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Cellular Response To Radiation Intrinsic Apoptotic Signaling Pathway Protein Propionyltransferase Activity Histone H3K27 Acetyltransferase Activity Peptide Crotonyltransferase Activity N-terminal Peptidyl-lysine Acetylation Histone H3K18 Acetyltransferase Activity Thigmotaxis Peptide Lactyltransferase (CoA-dependent) Activity Negative Regulation Of DNA Damage Checkpoint Protein Stabilization Negative Regulation Of Protein Oligomerization Vitamin D Receptor Signaling Pathway Cellular Response To Bisphenol A Transcription Coactivator Activity Positive Regulation Of RNA Biosynthetic Process L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Transferase Activity Positive Regulation Of DNA-templated Transcription Apoptotic Signaling Pathway Cell Dedifferentiation Response To Bisphenol A Regulation Of Protein Stability Intracellular Signal Transduction
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