MMP10

Gene Name		matrix metallopeptidase 10 (stromelysin 2)
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Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space
	Molecular Function	Metalloendopeptidase Activity Calcium Ion Binding Zinc Ion Binding
	Biological Process	Proteolysis Extracellular Matrix Disassembly Extracellular Matrix Organization Regulation Of Cell Migration Collagen Catabolic Process
Pathways		Collagen degradation Activation of Matrix Metalloproteinases Degradation of the extracellular matrix
Drugs
Diseases
GWAS		Multiple sclerosis ( 23412934) Prostate cancer ( 23535732)
Protein-protein Interactions		3 interactors: BCAN HAPLN1 MMP9
Entrez ID		4319
HPRD ID		01704
Ensembl ID		ENSG00000166670
Uniprot IDs		P09238
PDB IDs		1Q3A 3V96
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Skeletal System Development Extracellular Matrix Disassembly Positive Regulation Of Receptor Binding Positive Regulation Of Keratinocyte Migration Nervous System Development Dermatan Sulfate Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Metabolic Process Chondroitin Sulfate Catabolic Process Negative Regulation Of Cation Channel Activity Macrophage Differentiation Chondroitin Sulfate Biosynthetic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process Endodermal Cell Differentiation Central Nervous System Development Negative Regulation Of Transporter Activity System Development Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transmembrane Transport Endoderm Formation Proteoglycan Biosynthetic Process Glycosaminoglycan Catabolic Process Cell Adhesion Chondroitin Sulfate Metabolic Process Collagen Catabolic Process Multicellular Organismal Development Positive Regulation Of Protein Binding Hippocampus Development Anatomical Structure Development Regulation Of Cation Channel Activity Embryo Implantation Collagen Metabolic Process Positive Regulation Of Epithelial Cell Migration Multicellular Organismal Macromolecule Metabolic Process Endoderm Development Multicellular Organismal Metabolic Process Negative Regulation Of Ion Transport Limbic System Development Ephrin Receptor Signaling Pathway Glycosaminoglycan Biosynthetic Process Developmental Process Proteoglycan Metabolic Process Myeloid Leukocyte Differentiation Positive Regulation Of Binding Catabolic Process Formation Of Primary Germ Layer Regulation Of Ion Transmembrane Transporter Activity Regulation Of Epithelial Cell Migration
Tagcloud ?		affecting bad biochemical blotting cadherin compartments concomitant conveys cxcr4 delay elisa extracellular herein invasion jnk matrix mcf7 mek obtain overexpressing ras reporter semi sirna snail sp1 stats tlmp2 valuable