MMP10

Description		matrix metallopeptidase 10
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix
	Molecular Function	Endopeptidase Activity Metalloendopeptidase Activity Serine-type Endopeptidase Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Proteolysis Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process
Pathways		Collagen degradation Collagen degradation Degradation of the extracellular matrix Degradation of the extracellular matrix Activation of Matrix Metalloproteinases
Drugs		Marimastat N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID
Diseases
GWAS		Blood protein levels ( 30072576) Multiple sclerosis ( 23412934) Prostate cancer ( 23535732)
Novel Interacting Genes		1 novel interacting genes: TP53
Interacting Genes		3 interacting genes: BCAN HAPLN1 MMP9
Entrez ID		4319
HPRD ID		01704
Ensembl ID		ENSG00000166670
Uniprot IDs		P09238
PDB IDs		1Q3A 3V96 4ILW
Enriched GO Terms of Interacting Partners?		Perineuronal Net Central Nervous System Development Skeletal System Development Hyaluronic Acid Binding System Development Positive Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Release Of Cytochrome C From Mitochondria Extracellular Matrix Cellular Response To UV Cellular Response To Light Stimulus Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Regulation Of Mitochondrion Organization Response To UV Cellular Response To Radiation Regulation Of Intrinsic Apoptotic Signaling Pathway Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Negative Regulation Of Pentose-phosphate Shunt Oxidative Stress-induced Premature Senescence Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Glucose Catabolic Process To Lactate Via Pyruvate Germ Cell Nucleus Cellular Response To Actinomycin D Negative Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Positive Regulation Of Thymocyte Apoptotic Process Response To Actinomycin D T Cell Proliferation Involved In Immune Response Histone Deacetylase Regulator Activity Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Regulation Of G1 To G0 Transition Glial Cell Apoptotic Process Cellular Response To UV-C ATP-dependent DNA/DNA Annealing Activity B Cell Lineage Commitment Regulation Of Pentose-phosphate Shunt Mitochondrial DNA Repair Bone Marrow Development Stress-induced Premature Senescence Regulation Of NADP Metabolic Process Negative Regulation Of MiRNA Processing Mononuclear Cell Differentiation Response To Light Stimulus Cellular Response To UV-A Extracellular Space TFIID-class Transcription Factor Complex Binding Positive Regulation Of Programmed Necrotic Cell Death Cellular Response To Antibiotic Extracellular Matrix Structural Constituent Conferring Compression Resistance
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