TRPM1

Description		transient receptor potential cation channel subfamily M member 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Axon Cell Projection
	Molecular Function	Monoatomic Ion Channel Activity Monoatomic Cation Channel Activity Calcium Channel Activity Protein Binding Monoatomic Cation Transmembrane Transporter Activity Metal Ion Transmembrane Transporter Activity
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport G Protein-coupled Glutamate Receptor Signaling Pathway Visual Perception Monoatomic Ion Transmembrane Transport Protein Tetramerization Transmembrane Transport Calcium Ion Transmembrane Transport Cellular Response To Light Stimulus Monoatomic Cation Transmembrane Transport Calcium Ion Import Across Plasma Membrane
Pathways		TRP channels Regulation of MITF-M-dependent genes involved in apoptosis
Drugs
Diseases		Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO)
GWAS		Advanced age-related macular degeneration ( 28813576) Alzheimer's disease (late onset) ( 30820047) Huntington's disease progression ( 28642124) Hypertriglyceridemia ( 23505323) Macular thickness ( 30535121) Refractive error ( 32231278) Response to antipsychotic treatment ( 19721433) Type 2 diabetes ( 30130595)
Interacting Genes		1 interacting genes: FXR1
Entrez ID		4308
HPRD ID		04656
Ensembl ID		ENSG00000134160
Uniprot IDs		Q7Z4N2
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Strand Annealing Activity Positive Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Long-term Synaptic Potentiation Nuclear Pore Localization Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of MiRNA-mediated Gene Silencing Intracellular Membraneless Organelle Nuclear Pore Complex Assembly Costamere Ribonucleoprotein Granule Nuclear Pore Organization Skeletal Muscle Organ Development Translation Regulator Activity Regulation Of Circadian Sleep/wake Cycle, Sleep Pore Complex Assembly MRNA 3'-UTR AU-rich Region Binding Dentate Gyrus Development Regulation Of Circadian Sleep/wake Cycle Regulation Of Post-transcriptional Gene Silencing Regulation Of MiRNA-mediated Gene Silencing Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Rho Protein Signal Transduction Cytoplasmic Translational Initiation Ribonucleoprotein Complex Binding Presynaptic Modulation Of Chemical Synaptic Transmission Regulation Of Long-term Synaptic Potentiation Molecular Condensate Scaffold Activity Regulation Of Neuronal Synaptic Plasticity Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Protein-containing Complex Localization Positive Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Behavior Negative Regulation Of MRNA Catabolic Process Translational Initiation Cytoplasmic Ribonucleoprotein Granule Regulation Of Rho Protein Signal Transduction Nucleus Organization Cytoplasmic Stress Granule Negative Regulation Of RNA Catabolic Process MRNA Destabilization Spermatid Development RNA Destabilization Negative Regulation Of MRNA Metabolic Process Positive Regulation Of MRNA Catabolic Process Regulation Of Circadian Rhythm Muscle Organ Development MRNA 3'-UTR Binding MRNA Transport
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