MGAT1

Description		alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome Extracellular Vesicle
	Molecular Function	Alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase Activity Protein Binding Acetylglucosaminyltransferase Activity Transferase Activity Glycosyltransferase Activity Manganese Ion Binding Metal Ion Binding
	Biological Process	In Utero Embryonic Development UDP-N-acetylglucosamine Catabolic Process Protein Glycosylation Protein N-linked Glycosylation Protein N-linked Glycosylation Via Asparagine Viral Protein Processing
Pathways		N-glycan trimming and elongation in the cis-Golgi Maturation of spike protein Maturation of spike protein
Drugs		Uridine-Diphosphate-N-Acetylglucosamine
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32759990) Quantitative traits ( 19197348) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Weight ( 19851299)
Interacting Genes		2 interacting genes: MAPK6 SMAD9
Entrez ID		4245
HPRD ID		01189
Ensembl ID		ENSG00000131446
Uniprot IDs		P26572
PDB IDs
Enriched GO Terms of Interacting Partners?		Septin Cytoskeleton Heteromeric SMAD Protein Complex SMAD Protein Complex I-SMAD Binding MAP Kinase Activity SMAD Protein Signal Transduction Intracellular Signaling Cassette Cellular Response To BMP Stimulus Positive Regulation Of Dendritic Spine Development
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