MGAT1

Gene Name		mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Membrane Integral Component Of Membrane Vesicle Extracellular Vesicular Exosome
	Molecular Function	Alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase Activity Acetylglucosaminyltransferase Activity Metal Ion Binding
	Biological Process	In Utero Embryonic Development Carbohydrate Metabolic Process UDP-N-acetylglucosamine Catabolic Process Protein Glycosylation Protein N-linked Glycosylation Via Asparagine Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Defective ALG2 causes ALG2-CDG (CDG-1i) Diseases of glycosylation Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Transport to the Golgi and subsequent modification Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Defective MOGS causes MOGS-CDG (CDG-2b) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective MAN1B1 causes MRT15 Defective ALG12 causes ALG12-CDG (CDG-1g) N-glycan trimming and elongation in the cis-Golgi Diseases associated with N-glycosylation of proteins Defective ALG11 causes ALG11-CDG (CDG-1p)
Drugs
Diseases
GWAS		Quantitative traits ( 19197348) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Weight ( 19851299)
Protein-protein Interactions		2 interactors: MAPK6 SMAD9
Entrez ID		4245
HPRD ID		01189
Ensembl ID		ENSG00000131446
Uniprot IDs		P26572
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?		adipose c57bl carrier ccr2 cd11b cd11c cd36 cd68 cga chlorogenic chow coffee curbed dmso drinking f4 fabp4 hepatic hfd mcp obese obesity peritoneal ppargamma preventive regular steatosis twice weekly