ME2

Gene Name		malic enzyme 2, NAD(+)-dependent, mitochondrial
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Intracellular Membrane-bounded Organelle
	Molecular Function	Malate Dehydrogenase (decarboxylating) (NAD+) Activity Oxaloacetate Decarboxylase Activity Electron Carrier Activity Metal Ion Binding NAD Binding
	Biological Process	Malate Metabolic Process Oxidation-reduction Process
Pathways
Drugs		NADH Fumarate Nicotinamide-Adenine-Dinucleotide Malate Ion Alpha-Ketomalonic Acid Tartronate
Diseases
GWAS		Entorhinal cortical thickness ( 21116278)
Protein-protein Interactions		1 interactors: DYNLL1
Entrez ID		4200
HPRD ID		01103
Ensembl ID
Uniprot IDs		P23368
PDB IDs		1DO8 1EFK 1EFL 1GZ3 1GZ4 1PJ2 1PJ3 1PJ4 1PJL 1QR6
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Substantia Nigra Development Neural Nucleus Development Positive Regulation Of Mitochondrion Organization Midbrain Development Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Regulation Of Mitochondrion Organization Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Female Gamete Generation G2/M Transition Of Mitotic Cell Cycle
Tagcloud ?		acts amphetamine analog autoreceptors blocker cation cocaine di dopamine efflux endogenously freely hydroxy intensified me2nh microdialysis moving mpp nh norharmanium perfusion phenyl phenylpyridinium propylpiperidine releaser reuptake striatum tetrodotoxin transporter