EPCAM

Name	epithelial cell adhesion molecule
Structure
Interactors	2 interactors: CLDN7 TSC22D2
GO Annotations	Cellular Component	Plasma Membrane Bicellular Tight Junction Cell Surface Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Extracellular Exosome Anchoring Junction
	Molecular Function	Protein Binding Protein-containing Complex Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Ureteric Bud Development Positive Regulation Of Cell Population Proliferation Signal Transduction Involved In Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Stem Cell Differentiation Cell-cell Adhesion Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Stem Cell Proliferation
Pathways	Cell surface interactions at the vascular wall Attachment of bacteria to epithelial cells Developmental Lineage of Mammary Gland Luminal Epithelial Cells Developmental Lineage of Mammary Gland Alveolar Cells Developmental Lineage of Mammary Gland Myoepithelial Cells Developmental Lineage of Mammary Stem Cells
Drugs	Oportuzumab monatox ING-1 Catumaxomab Technetium Tc-99m nofetumomab merpentan Hypromellose
Diseases	Mismatch repair deficiency, including: Hereditary non-polyposis colorectal cancer (HNPCC); Lynch syndrome; Muir-Torre syndrome; Turcot syndrome
GWAS	epithelial cell adhesion molecule levels ( 25147954 ) Severe insulin-deficient type 2 diabetes ( 34737425 )
Entrez ID	4072
HPRD ID	01709
Ensembl ID	ENSG00000119888
Uniprot IDs	P16422
PDB IDs	4MZV 6I07