MIR24-1

Description		microRNA 24-1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space RISC Complex Extracellular Exosome Extracellular Vesicle
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration Negative Regulation Of Type II Interferon Production MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Osteoblast Differentiation Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Amyloid-beta Formation Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Negative Regulation Of Sodium Ion Import Across Plasma Membrane Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Negative Regulation Of Macrophage Migration Negative Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of Fibroblast Apoptotic Process Positive Regulation Of Endothelial Cell Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes		1 interacting genes: AGO2
Entrez ID		407012
HPRD ID
Ensembl ID		ENSG00000284459
Uniprot IDs
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoribonuclease Activity, Cleaving MiRNA-paired MRNA MRNA Cap Binding Endoribonuclease Activity, Cleaving SiRNA-paired MRNA SiRNA-mediated Gene Silencing By MRNA Destabilization RNA Endonuclease Activity Producing 5'-phosphomonoesters, Hydrolytic Mechanism RISC-loading Complex SiRNA Binding Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RISC Complex Assembly SiRNA Processing RNA 7-methylguanosine Cap Binding Negative Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Trophoblast Cell Migration Pre-miRNA Processing Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Negative Regulation Of Glycoprotein Metabolic Process Regulation Of Amyloid Precursor Protein Biosynthetic Process P-body Assembly Core Promoter Sequence-specific DNA Binding Regulation Of Trophoblast Cell Migration Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MiRNA Metabolic Process MRNA 3'-UTR AU-rich Region Binding Regulation Of Synapse Maturation RNA Polymerase II Complex Binding MiRNA Processing MiRNA Binding RNA Endonuclease Activity MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Glycoprotein Biosynthetic Process Negative Regulation Of Translational Initiation Single-stranded RNA Binding Translation Initiation Factor Activity MiRNA-mediated Gene Silencing By Inhibition Of Translation Double-stranded RNA Binding Endonuclease Activity Post-embryonic Development RNA Stabilization Positive Regulation Of Reproductive Process Translational Initiation Cytoplasmic Ribonucleoprotein Granule RISC Complex MRNA Destabilization Negative Regulation Of RNA Catabolic Process P-body RNA Destabilization Regulation Of Translational Initiation Positive Regulation Of MRNA Catabolic Process MiRNA-mediated Post-transcriptional Gene Silencing
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