MIR199A1

Description		microRNA 199a-1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space RISC Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	Re-entry Into Mitotic Cell Cycle Negative Regulation Of Receptor Internalization Positive Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Autophagy Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Gene Expression Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Low-density Lipoprotein Particle Clearance Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of BMP Signaling Pathway Positive Regulation Of TOR Signaling Negative Regulation Of Hepatocyte Growth Factor Production MiRNA-mediated Post-transcriptional Gene Silencing Negative Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Myoblast Differentiation Regulation Of Angiogenesis Positive Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of SMAD Protein Signal Transduction Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Lung Blood Pressure Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Matrix Metallopeptidase Secretion Positive Regulation Of Cardiac Muscle Tissue Regeneration Regulation Of Connective Tissue Replacement Positive Regulation Of Connective Tissue Replacement Positive Regulation Of Myoblast Proliferation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Interacting Genes		83 interacting genes: AIMP1 AIMP2 C1QBP CELF1 CELF2 CPSF1 CPSF6 CPSF7 DARS1 DDX1 DDX21 DDX3X DDX49 DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FUS HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SAFB SF3A3 SF3B1 SF3B2 SF3B3 SFPQ SPOUT1 STRBP SYMPK SYNCRIP TAF15 TIAL1 TRA2A TRA2B UPF1 UTP20 YBX1 YBX2 YBX3
Entrez ID		406976
HPRD ID
Ensembl ID		ENSG00000207752
Uniprot IDs
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process MRNA Processing RNA Splicing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process Macromolecule Metabolic Process Regulation Of RNA Splicing MRNA Binding Aminoacyl-tRNA Synthetase Multienzyme Complex Post-transcriptional Regulation Of Gene Expression Nucleus Ribonucleoprotein Complex Nucleoplasm MRNA 3'-UTR Binding Regulation Of MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Translation Regulation Of MRNA Splicing, Via Spliceosome Cytoplasmic Stress Granule Catalytic Step 2 Spliceosome Spliceosomal Complex MiRNA Binding Negative Regulation Of MRNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Stability TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of Macromolecule Metabolic Process Negative Regulation Of Translation TRNA Aminoacylation Regulation Of MRNA Stability Regulation Of Primary Metabolic Process Negative Regulation Of RNA Catabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of Metabolic Process Ligase Activity MRNA Stabilization Regulation Of RNA Metabolic Process TRNA Metabolic Process Pre-mRNA Binding Positive Regulation Of Cytoplasmic Translation
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