MIR122

Description		microRNA 122
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space RISC Complex Extracellular Exosome Extracellular Vesicle
	Molecular Function
	Biological Process	MiRNA-mediated Post-transcriptional Gene Silencing
Pathways
Drugs
Diseases
GWAS		Gamma glutamyl transferase levels ( 29403010 33339817) High density lipoprotein cholesterol levels ( 29083408) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Platelet count ( 32888494) Plateletcrit ( 32888494) Serum alkaline phosphatase levels ( 33339817)
Interacting Genes		70 interacting genes: AIMP1 AIMP2 C1QBP CPSF1 DARS1 DDX1 DDX21 DDX3X DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LIN28A LIN28B LRPPRC MARS1 MATR3 NOL6 NONO NUDT16L1 NUDT21 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PURA QARS1 RARS1 RBFOX2 RBM14 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SFPQ STRBP SYNCRIP TAF15 TENT2 TRA2A TRA2B UPF1 UTP20 YBX1 YBX3 ZNF346
Entrez ID		406906
HPRD ID
Ensembl ID		ENSG00000284440
Uniprot IDs
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process RNA Splicing MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Regulation Of RNA Splicing Nucleus Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Binding Aminoacyl-tRNA Synthetase Multienzyme Complex Ribonucleoprotein Complex Nucleoplasm Spliceosomal Complex Catalytic Step 2 Spliceosome Post-transcriptional Regulation Of Gene Expression Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Catabolic Process Regulation Of MRNA Processing Negative Regulation Of MRNA Catabolic Process Regulation Of Gene Expression MRNA Stabilization Regulation Of Translation Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process RNA Stabilization Regulation Of Macromolecule Metabolic Process MRNA 3'-UTR Binding MiRNA Binding Negative Regulation Of Macromolecule Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Positive Regulation Of Gene Expression Negative Regulation Of Translation TRNA Aminoacylation CRD-mediated MRNA Stabilization Nucleolus Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Stability Negative Regulation Of Metabolic Process Ligase Activity Regulation Of Metabolic Process
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