LY75

Name	lymphocyte antigen 75
Structure
Novel Interactors	1 novel interactors: CDK4
Interactors	None recorded
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Binding Carbohydrate Binding Signaling Receptor Activity
	Biological Process	Endocytosis Inflammatory Response Immune Response
GWAS	Aspartate aminotransferase levels ( 33547301 ) Crohn's disease ( 26192919 ) Crohn's disease-related phenotypes ( 25557950 ) Idiopathic membranous nephropathy ( 21323541 ) Inflammatory bowel disease ( 26192919 ) Lymphocyte percentage of white cells ( 32888494 ) Mean corpuscular hemoglobin ( 32888494 ) Mean corpuscular volume ( 32888494 ) Mean platelet volume ( 32888494 ) Mean reticulocyte volume ( 32888494 ) Myeloid white cell count ( 27863252 ) Neutrophil count ( 29403010 32888494 ) Neutrophil percentage of white cells ( 32888494 ) Platelet count ( 29403010 32888494 27863252 ) Plateletcrit ( 27863252 32888494 ) Proportion of activated microglia (inferior temporal cortex) ( 30679421 ) Red blood cell count ( 32888494 ) Tourette syndrome ( 30818990 ) Waist circumference adjusted for body mass index ( 34021172 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 34021172 ) White blood cell count ( 32888494 29403010 )
Entrez ID	4065
HPRD ID	05161
Ensembl ID	ENSG00000054219
Uniprot IDs	O60449 Q59H44
PDB IDs	7JPT 7JPU 8HBC 8K8H
GO Terms Enriched among Interactors ?	Cyclin D2-CDK4 Complex Cyclin D1-CDK4 Complex Cyclin D3-CDK4 Complex Cellular Response To Ionomycin Cellular Response To Ether Regulation Of Type B Pancreatic Cell Proliferation Response To Phorbol 13-acetate 12-myristate Cellular Response To Phorbol 13-acetate 12-myristate Positive Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Response To Interleukin-4 Cyclin Binding Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Response To Interleukin-4 Response To Ether Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Cellular Response To Fatty Acid Cyclin-dependent Protein Kinase Holoenzyme Complex Positive Regulation Of Fibroblast Proliferation Response To Fatty Acid Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of Fibroblast Proliferation Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle G2/M Phase Transition Bicellular Tight Junction Positive Regulation Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Response To Ketone Transcription Regulator Complex Positive Regulation Of Cell Cycle Process Nuclear Membrane Response To Alcohol Response To Xenobiotic Stimulus Response To Lipopolysaccharide Response To Molecule Of Bacterial Origin Positive Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Protein Serine Kinase Activity Regulation Of Epithelial Cell Proliferation Protein Serine/threonine Kinase Activity