LSAMP

Description		limbic system associated membrane protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Membrane Side Of Membrane
	Molecular Function	Protein Binding
	Biological Process	Cell Adhesion Nervous System Development
Pathways		Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Blood protein levels ( 30072576) BMI x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429) Chronotype ( 30696823) Colorectal or endometrial cancer ( 26621817) Emphysema imaging phenotypes ( 26030696) Experiencing mood swings ( 29500382) Feeling miserable ( 29500382) Fish- and plant-related diet ( 32066663) General factor of neuroticism ( 30867560) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hip circumference ( 28552196) Itch intensity from mosquito bite adjusted by bite size ( 28199695) L1-L4 bone mineral density x serum urate levels interaction ( 34046847) Systemising ( 31508503) Tourette's syndrome or obsessive-compulsive disorder ( 25158072) Triglyceride levels ( 34074324)
Novel Interacting Genes		1 novel interacting genes: ATP6V1A
Interacting Genes		3 interacting genes: NEGR1 NTM PRNP
Entrez ID		4045
HPRD ID		09128
Ensembl ID		ENSG00000185565
Uniprot IDs		B7Z661 Q13449
PDB IDs
Enriched GO Terms of Interacting Partners?		Side Of Membrane Positive Regulation Of Calcium-mediated Signaling Type 8 Metabotropic Glutamate Receptor Binding Regulation Of Calcium-mediated Signaling ATPase Complex Proton-transporting V-type ATPase, V1 Domain Intracellular Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Extrinsic Component Of Synaptic Vesicle Membrane Proton-transporting Two-sector ATPase Complex Golgi Lumen Acidification Synaptic Vesicle Lumen Acidification Vacuolar Proton-transporting V-type ATPase, V1 Domain Proton-transporting V-type ATPase Complex Intracellular Monoatomic Cation Homeostasis Endosomal Lumen Acidification Chemical Homeostasis Inorganic Ion Homeostasis Homeostatic Process Cellular Response To Increased Oxygen Levels ATP-dependent Protein Binding Negative Regulation Of Calcineurin-NFAT Signaling Cascade Positive Regulation Of Glutamate Receptor Signaling Pathway Postsynaptic Density Inclusion Body Regulation Of Calcium Ion Import Across Plasma Membrane Neuron Projection Maintenance Negative Regulation Of Interleukin-17 Production Negative Regulation Of Dendritic Spine Maintenance Regulation Of Dendritic Spine Maintenance Extrinsic Component Of Membrane Negative Regulation Of Long-term Synaptic Potentiation Aspartic-type Endopeptidase Inhibitor Activity Intracellular Copper Ion Homeostasis Dendrite Dendritic Spine Maintenance Cuprous Ion Binding Cupric Ion Binding Regulation Of Glutamate Receptor Signaling Pathway Copper Ion Homeostasis Regulation Of Synapse Organization Negative Regulation Of Activated T Cell Proliferation Lamin Binding Type 5 Metabotropic Glutamate Receptor Binding Apical Dendrite Lipid Droplet Formation Positive Regulation Of Saliva Secretion Negative Regulation Of Synapse Organization Positive Regulation Of Digestive System Process Negative Regulation Of Synapse Assembly
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