PHOX2A

Name	paired like homeobox 2A
Structure	No pdb structure
Interactors	5 interactors: ATF6B CREBBP HAND2 JUN PRKACA
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Noradrenergic Neuron Differentiation Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Somatic Motor Neuron Differentiation Oculomotor Nerve Formation Trochlear Nerve Formation Locus Ceruleus Development Midbrain Development Regulation Of Respiratory Gaseous Exchange Positive Regulation Of Transcription By RNA Polymerase II Sympathetic Nervous System Development Parasympathetic Nervous System Development Neuron Development Dopaminergic Neuron Differentiation
Diseases	Congenital fibrosis of the extraocular muscles (CFEOM)
GWAS	No GWAS studies recorded
Entrez ID	401
HPRD ID	04129
Ensembl ID	ENSG00000165462
Uniprot IDs	O14813
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Transcription Regulator Complex RNA Polymerase II-specific DNA-binding Transcription Factor Binding Transcription Cis-regulatory Region Binding Positive Regulation Of Biosynthetic Process Embryonic Digit Morphogenesis Transcription Coactivator Binding Chromatin Positive Regulation Of Transcription By RNA Polymerase II Outflow Tract Morphogenesis DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Signal Transduction Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Signal Transduction Positive Regulation Of Cell Communication Regulation Of Cell Communication Positive Regulation Of RNA Biosynthetic Process Regulation Of Smoothened Signaling Pathway Cellular Response To Stress Positive Regulation Of DNA-templated Transcription Intracellular Signal Transduction Positive Regulation Of Signaling Histone H3K27 Acetyltransferase Activity Regulation Of Signaling Positive Regulation Of RNA Metabolic Process Negative Regulation Of ATF6-mediated Unfolded Protein Response Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity RNA Polymerase II Transcription Regulator Complex Leading Edge Cell Differentiation Primary Palate Development Positive Regulation Of Semaphorin-plexin Signaling Pathway Cell Proliferation Involved In Outflow Tract Morphogenesis Visceral Serous Pericardium Development Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Peptide Lactyltransferase (CoA-dependent) Activity Regulation Of Intracellular Signal Transduction Cellular Response To Anisomycin Regulation Of Osteoblast Differentiation Regulation Of Semaphorin-plexin Signaling Pathway Intracellular Signaling Cassette Regulation Of ATF6-mediated Unfolded Protein Response Response To Anisomycin Anatomical Structure Formation Involved In Morphogenesis Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Protein Localization To Lipid Droplet Cardiac Neural Crest Cell Development Involved In Outflow Tract Morphogenesis