PAIP2B

Description		poly(A) binding protein interacting protein 2B
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	MRNA Regulatory Element Binding Translation Repressor Activity Protein Binding Translation Repressor Activity
	Biological Process	Regulation Of Translation Negative Regulation Of Translation Negative Regulation Of Translational Initiation
Pathways
Drugs
Diseases
GWAS		Extremely high intelligence ( 29520040) Metabolite levels ( 23823483) Pulse pressure ( 27841878) QRS interval (sulfonylurea treatment interaction) ( 27958378) Survival in pancreatic cancer ( 28470677)
Interacting Genes		1 interacting genes: PABPC1
Entrez ID		400961
HPRD ID		19285
Ensembl ID		ENSG00000124374
Uniprot IDs		Q9ULR5
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Translation Activator Activity MCRD-mediated MRNA Stability Complex Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay CRD-mediated MRNA Stabilization Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Poly(U) RNA Binding Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Cytoplasmic Translation Poly(A) Binding Positive Regulation Of Viral Genome Replication Regulation Of Cytoplasmic Translation Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cell Leading Edge Positive Regulation Of Viral Process MRNA Stabilization Negative Regulation Of MRNA Catabolic Process Regulation Of Viral Genome Replication RNA Stabilization Cytoplasmic Ribonucleoprotein Granule Catalytic Step 2 Spliceosome Negative Regulation Of RNA Catabolic Process Cytoplasmic Stress Granule Negative Regulation Of MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process Positive Regulation Of MRNA Catabolic Process Regulation Of Viral Life Cycle MRNA 3'-UTR Binding MRNA Catabolic Process Regulation Of Viral Process Positive Regulation Of MRNA Metabolic Process Positive Regulation Of Translation Regulatory NcRNA-mediated Gene Silencing Spliceosomal Complex RNA Catabolic Process Regulation Of MRNA Stability RNA Splicing, Via Transesterification Reactions Regulation Of RNA Stability MRNA Splicing, Via Spliceosome Lamellipodium MRNA Binding Regulation Of MRNA Metabolic Process Nucleobase-containing Compound Catabolic Process RNA Splicing Negative Regulation Of Catabolic Process Ribonucleoprotein Complex
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