SNX19

Description		sorting nexin 19
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Lipid Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Binding
	Biological Process	Chondrocyte Differentiation Exocytosis Protein Transport Insulin Secretion Establishment Of Localization In Cell Dense Core Granule Maturation
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Femur bone mineral density x serum urate levels interaction ( 34046847) Metabolite levels ( 23823483) Pulse pressure ( 27841878 30224653 30578418) Schizophrenia ( 23974872 25056061 28991256 29483656 30285260)
Novel Interacting Genes		1 novel interacting genes: CASP8
Interacting Genes		2 interacting genes: NOTCH3 PTPRN
Entrez ID		399979
HPRD ID		18621
Ensembl ID		ENSG00000120451
Uniprot IDs		B7ZAU9 E9PJV7 E9PLV3 Q92543
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Anesthetic Ripoptosome Death Effector Domain Binding Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Death-inducing Signaling Complex Angiogenesis CD95 Death-inducing Signaling Complex Glomerular Capillary Formation Neuroblast Differentiation Dense Core Granule Maturation Secretory Granule Maturation Positive Regulation Of Type B Pancreatic Cell Proliferation Positive Regulation Of Pyroptotic Inflammatory Response Self Proteolysis Response To Cobalt Ion TRAIL-activated Apoptotic Signaling Pathway Luteinization Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Type B Pancreatic Cell Proliferation Positive Regulation Of Execution Phase Of Apoptosis Positive Regulation Of Biosynthetic Process Positive Regulation Of Macrophage Differentiation Death Receptor Binding Negative Regulation Of Necroptotic Process Negative Regulation Of Programmed Necrotic Cell Death Positive Regulation Of Macromolecule Biosynthetic Process Transcription Factor Binding Cell Differentiation Involved In Embryonic Placenta Development Regulation Of Macrophage Differentiation Execution Phase Of Apoptosis Ubiquitin-like Protein Ligase Binding Spectrin Binding
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