LHX1

Gene Name		LIM homeobox 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Protein Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Urogenital System Development Ureteric Bud Development Branching Involved In Ureteric Bud Morphogenesis Gastrulation With Mouth Forming Second Ectoderm Formation Endoderm Formation Kidney Development Transcription From RNA Polymerase II Promoter Cell-cell Signaling Pattern Specification Process Nervous System Development Motor Neuron Axon Guidance Anatomical Structure Morphogenesis Post-embryonic Development Embryonic Pattern Specification Organ Morphogenesis Anterior/posterior Axis Specification Anterior/posterior Pattern Specification Dorsal/ventral Pattern Formation Regulation Of Gene Expression Retina Layer Formation Ventral Spinal Cord Development Spinal Cord Association Neuron Differentiation Telencephalon Development Cerebellum Development Cerebellar Purkinje Cell Differentiation Forebrain Regionalization Cerebellar Purkinje Cell-granule Cell Precursor Cell Signaling Involved In Regulation Of Granule Cell Precursor Cell Proliferation Somite Rostral/caudal Axis Specification Metanephric Part Of Ureteric Bud Development Oviduct Epithelium Development Uterine Epithelium Development Nephric Duct Elongation Horizontal Cell Localization Positive Regulation Of Embryonic Development Cellular Response To Fibroblast Growth Factor Stimulus Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Anatomical Structure Formation Involved In Morphogenesis Embryonic Viscerocranium Morphogenesis Pronephros Development Embryonic Retina Morphogenesis In Camera-type Eye Uterus Development Oviduct Development Cervix Development Vagina Development Head Development Epithelium Development Paramesonephric Duct Development Comma-shaped Body Morphogenesis S-shaped Body Morphogenesis Renal Vesicle Morphogenesis Mesonephric Duct Development Nephric Duct Morphogenesis Metanephric Glomerulus Development Metanephric Comma-shaped Body Morphogenesis Metanephric Renal Vesicle Morphogenesis Metanephric S-shaped Body Morphogenesis Primitive Streak Formation Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Lateral Motor Column Neuron Migration Positive Regulation Of Gastrulation Positive Regulation Of Anterior Head Development Positive Regulation Of Nephron Tubule Epithelial Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: FOXA2 ISL1 LHX3 OTX2 RLIM
Entrez ID		3975
HPRD ID		09067
Ensembl ID		ENSG00000132130
Uniprot IDs		P48742 Q58F18
PDB IDs
Enriched GO Terms of Interacting Partners?		Neuron Fate Commitment Cell Fate Specification Neuron Fate Specification Cell Fate Commitment Diencephalon Development Pattern Specification Process Positive Regulation Of Gastrulation Dorsal/ventral Pattern Formation Primitive Streak Formation Regulation Of Transcription From RNA Polymerase II Promoter Somite Rostral/caudal Axis Specification Spinal Cord Motor Neuron Cell Fate Specification Brain Development Head Development Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Central Nervous System Development Organ Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Embryonic Development Regulation Of Gastrulation Neuron Differentiation Spinal Cord Motor Neuron Differentiation Axon Guidance Cell Fate Determination Embryonic Axis Specification Positive Regulation Of Transcription, DNA-templated RNA Metabolic Process Pituitary Gland Development Gastrulation With Mouth Forming Second Ventral Spinal Cord Development Forebrain Development Gene Expression Cell Differentiation In Spinal Cord Positive Regulation Of Macromolecule Biosynthetic Process Anterior/posterior Axis Specification Cellular Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Generation Of Neurons Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Axonogenesis Neurogenesis Somitogenesis Embryonic Pattern Specification Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Regulation Of Smoothened Signaling Pathway
Tagcloud ?		activin atp1b1 belongs bip caps elusive folding grp78 homeobox hspa5 hspa5mo knock lim malformation morphants morpholino mos multifunctional oligonucleotides participates pax2 pronephric pronephros rescued residing serves specification unfolded xenopus